Literature summary for 2.4.1.232 extracted from

Du, T.; Ouyang, H.; Voglmeir, J.; Wilson, I.B.H.; Jin, C.
Aspergillus fumigatus Mnn9 is responsible for mannan synthesis and required for covalent linkage of mannoprotein to the cell wall (2019), Fungal Genet. Biol., 128, 20-28 .

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Organism

Organism	UniProt	Comment	Textmining
Aspergillus fumigatus	Q4WIL2	i.e. Aspergillus fumigatus strain YJ-407	-
Aspergillus fumigatus ATCC MYA-4609	Q4WIL2	i.e. Aspergillus fumigatus strain YJ-407	-

Synonyms

Synonyms	Comment	Organism
AFUA_2G01450	genme name	Aspergillus fumigatus
Mnn9	-	Aspergillus fumigatus

General Information

General Information	Comment	Organism
malfunction	deletion of the mnn9 gene results in an increased sensitivity to calcofluor white, Congo red, or hygromycin B as well as in reduced cell wall components and abnormal polarity. Although there is no major effect on N-glycan synthesis, covalently-linked cell wall mannoprotein Mp1 is significantly reduced in the mutant	Aspergillus fumigatus
physiological function	Mnn9 is required for mannan and mannoprotein biosynthesis. The enzyme is essential for cell wall integrity, morphogenesis, and proper localization of cell wall mannoprotein	Aspergillus fumigatus

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Release 2023.1 (January 2023)