Literature summary for 2.4.1.145 extracted from

Ide, Y.; Miyoshi, E.; Nakagawa, T.; Gu, J.; Tanemura, M.; Nishida, T.; Ito, T.; Yamamoto, H.; Kozutsumi, Y.; Taniguchi, N.
Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer (2006), Biochem. Biophys. Res. Commun., 341, 478-482.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q9UM21	-	-
Homo sapiens	Q9UQ53	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
pancreatic cancer cell line	Panc-1, PCI6, MIA PaCa-2, and BxPC3. Down-regulation of GnT-IVa in pancreatic cancer cells is due to an epigenetic abnormality in the gene. When pancreatic cancer cells are treated with 5-aza-C or butyrate, the expression of GnT-IVa is dramatically increased	Homo sapiens	-
pancreatic cancer cell line	Panc-1, PCI6, MIA PaCa-2, and BxPC3. Expression of GnT-IVb is increased in pancreatic cancer, compared to normal pancreatic tissues	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
GnT-IVa	-	Homo sapiens
GnT-IVb	-	Homo sapiens
N-acetylglucosaminyltransferase-IVa	-	Homo sapiens
N-acetylglucosaminyltransferase-IVb	-	Homo sapiens

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Release 2023.1 (January 2023)