Activating Compound | Comment | Organism | Structure |
---|---|---|---|
RodA | RodA is required for isoform PBP2 activity | Escherichia coli |
Crystallization (Comment) | Organism |
---|---|
- |
Staphylococcus aureus |
- |
Escherichia coli |
- |
Aquifex aeolicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
AC326-alpha | - |
Aquifex aeolicus | |
AC326-alpha | - |
Bacillus subtilis | |
AC326-alpha | - |
Caulobacter vibrioides | |
AC326-alpha | - |
Cereibacter sphaeroides | |
AC326-alpha | - |
Escherichia coli | |
AC326-alpha | - |
Mycobacterium tuberculosis | |
AC326-alpha | - |
Staphylococcus aureus | |
ACL19273 | - |
Aquifex aeolicus | |
ACL19273 | - |
Bacillus subtilis | |
ACL19273 | - |
Caulobacter vibrioides | |
ACL19273 | - |
Cereibacter sphaeroides | |
ACL19273 | - |
Escherichia coli | |
ACL19273 | - |
Mycobacterium tuberculosis | |
ACL19273 | - |
Staphylococcus aureus | |
Garneau-5 | - |
Aquifex aeolicus | |
Garneau-5 | - |
Bacillus subtilis | |
Garneau-5 | - |
Caulobacter vibrioides | |
Garneau-5 | - |
Cereibacter sphaeroides | |
Garneau-5 | - |
Escherichia coli | |
Garneau-5 | - |
Mycobacterium tuberculosis | |
Garneau-5 | - |
Staphylococcus aureus | |
HTS6 | - |
Aquifex aeolicus | |
HTS6 | - |
Bacillus subtilis | |
HTS6 | - |
Caulobacter vibrioides | |
HTS6 | - |
Cereibacter sphaeroides | |
HTS6 | - |
Escherichia coli | |
HTS6 | - |
Mycobacterium tuberculosis | |
HTS6 | - |
Staphylococcus aureus | |
HTS7 | - |
Aquifex aeolicus | |
HTS7 | - |
Bacillus subtilis | |
HTS7 | - |
Caulobacter vibrioides | |
HTS7 | - |
Cereibacter sphaeroides | |
HTS7 | - |
Escherichia coli | |
HTS7 | - |
Mycobacterium tuberculosis | |
HTS7 | - |
Staphylococcus aureus | |
HTS8 | - |
Aquifex aeolicus | |
HTS8 | - |
Bacillus subtilis | |
HTS8 | - |
Caulobacter vibrioides | |
HTS8 | - |
Cereibacter sphaeroides | |
HTS8 | - |
Escherichia coli | |
HTS8 | - |
Mycobacterium tuberculosis | |
HTS8 | - |
Staphylococcus aureus | |
moenomycin A | - |
Aquifex aeolicus | |
moenomycin A | - |
Bacillus subtilis | |
moenomycin A | - |
Caulobacter vibrioides | |
moenomycin A | - |
Cereibacter sphaeroides | |
moenomycin A | - |
Escherichia coli | |
moenomycin A | - |
Mycobacterium tuberculosis | |
moenomycin A | - |
Staphylococcus aureus | |
TS30153 | - |
Aquifex aeolicus | |
TS30153 | - |
Bacillus subtilis | |
TS30153 | - |
Caulobacter vibrioides | |
TS30153 | - |
Cereibacter sphaeroides | |
TS30153 | - |
Escherichia coli | |
TS30153 | - |
Mycobacterium tuberculosis | |
TS30153 | - |
Staphylococcus aureus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aquifex aeolicus | - |
- |
- |
Bacillus subtilis | - |
- |
- |
Caulobacter vibrioides | - |
- |
- |
Cereibacter sphaeroides | - |
- |
- |
Escherichia coli | - |
- |
- |
Mycobacterium tuberculosis | - |
- |
- |
Staphylococcus aureus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Staphylococcus aureus | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Bacillus subtilis | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Escherichia coli | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Cereibacter sphaeroides | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Mycobacterium tuberculosis | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Caulobacter vibrioides | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? | |
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol | - |
Aquifex aeolicus | [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PBP1 | isoform | Bacillus subtilis |
PBP1a | - |
Aquifex aeolicus |
PBP1a | isoform | Escherichia coli |
PBP1a | isoform | Caulobacter vibrioides |
PBP1b | isoform | Escherichia coli |
PBP2 | - |
Staphylococcus aureus |
PBP2 | isoform | Escherichia coli |
PBP2 | isoform | Cereibacter sphaeroides |
PBP2 | isoform | Caulobacter vibrioides |
PBP2A | isoform | Bacillus subtilis |
PBP2A | isoform | Caulobacter vibrioides |
PBP2b | isoform | Caulobacter vibrioides |
PBP2c | isoform | Bacillus subtilis |
PBP2d | isoform | Bacillus subtilis |
PBP3 | isoform | Bacillus subtilis |
PBP3 | isoform | Escherichia coli |
PBP4 | isoform | Bacillus subtilis |
PBP7 | isoform | Escherichia coli |
PBP8 | isoform | Escherichia coli |
PBPA | isoform | Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform PBP3 is required for localization of MurG to division site | Escherichia coli |