Activating Compound | Comment | Organism | Structure |
---|---|---|---|
AMP | - |
Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(beta-D-glucopyranosyl)-5-(hept-1-yn-1-yl)uracil | - |
Oryctolagus cuniculus | |
1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)uracil | - |
Oryctolagus cuniculus | |
1-(beta-D-glucopyranosyl)-5-ethynyluracil | cytotoxic effect on Hep-G2 cells | Oryctolagus cuniculus | |
1-(beta-D-glucopyranosyl)-5-iodouracil | - |
Oryctolagus cuniculus | |
3-(beta-D-glucopyranosyl)-6-pentyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one | - |
Oryctolagus cuniculus | |
3-(beta-D-glucopyranosyl)-6-propyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one | - |
Oryctolagus cuniculus | |
alpha-D-glucose | physiological inhibitor | Oryctolagus cuniculus | |
additional information | synthesis of glucopyranonucleosides in the 5-alkynyl- and 6-alkylfurano[2,3-d]pyrimidine series, overview | Oryctolagus cuniculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(1->4)-alpha-D-glucosyl]n + phosphate | Oryctolagus cuniculus | - |
[(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
muscle | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[(1->4)-alpha-D-glucosyl]n + phosphate | - |
Oryctolagus cuniculus | [(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
glycogen phosphorylase b | - |
Oryctolagus cuniculus |
GPb | - |
Oryctolagus cuniculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
assay at | Oryctolagus cuniculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.8 | - |
assay at | Oryctolagus cuniculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
1-(beta-D-glucopyranosyl)-5-iodouracil | pH 6.8, 30°C | Oryctolagus cuniculus | |
0.0047 | - |
1-(beta-D-glucopyranosyl)-5-ethynyluracil | pH 6.8, 30°C | Oryctolagus cuniculus | |
0.0324 | - |
3-(beta-D-glucopyranosyl)-6-propyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one | pH 6.8, 30°C | Oryctolagus cuniculus | |
0.0334 | - |
3-(beta-D-glucopyranosyl)-6-pentyl-2,3-dihydro-furano-[2,3-d]pyrimidin-2-one | pH 6.8, 30°C | Oryctolagus cuniculus | |
0.303 | - |
1-(beta-D-glucopyranosyl)-5-(pent-1-yn-1-yl)uracil | pH 6.8, 30°C | Oryctolagus cuniculus | |
1.7 | - |
alpha-D-glucose | pH 6.8, 30°C | Oryctolagus cuniculus | |
3.204 | - |
1-(beta-D-glucopyranosyl)-5-(hept-1-yn-1-yl)uracil | pH 6.8, 30°C | Oryctolagus cuniculus |
General Information | Comment | Organism |
---|---|---|
additional information | structural analysis of molecular elements that govern molecular recognition by the catalytic site of the enzyme with emphasis in the beta-pocket environment, overview | Oryctolagus cuniculus |