Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.3.13 extracted from

  • Bartholomew, J.C.; Calvo, J.M.
    alpha-Isopropylmalate synthase from Salmonella typhimurium. Carboxypeptidase digestion studies of parent and feedback-insensitive enzymes (1971), Biochim. Biophys. Acta, 250, 568-576.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
leucine the enzyme from the mutant strain CV241 is insensitive to feedback inhibition by Leu due to a mutation at the extreme operator-distal end of leuA Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhimurium
-
strain CV-123, and mutant strain CV-241 with a feed-back insensitive enzyme
-

Purification (Commentary)

Purification (Comment) Organism
-
Salmonella enterica subsp. enterica serovar Typhimurium

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.67
-
-
Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-oxo-3-methylbutanoate + acetyl-CoA + H2O
-
Salmonella enterica subsp. enterica serovar Typhimurium 3-hydroxy-4-methyl-3-carboxypentanoate + CoA
-
?