Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus pneumoniae | Q9K307 | penicillin-resistant strain | - |
Streptococcus pneumoniae | Q9L447 | penicillin-susceptible strain | - |
Streptococcus pneumoniae Pen6 | Q9K307 | penicillin-resistant strain | - |
Streptococcus pneumoniae R36A | Q9L447 | penicillin-susceptible strain | - |
General Information | Comment | Organism |
---|---|---|
physiological function | allelic replacement of the mosaic murM gene of strain Pen6 with murM of the penicillin-susceptible laboratory strain R36A causes enrichment of the peptidoglycan in linear muropeptides | Streptococcus pneumoniae |
physiological function | inactivation of the murMN operon by insertion duplication mutagenesis does not cause any significant change in growth rate of the cultures, but leads to the disappearance of all branched muropeptide monomers and dimers accompanied by a parallel increase in the percentage of linear structured stem peptides and in the appearance of novel peptide structures. Allelic replacement of the mosaic murM gene of strain Pen6 with murM of the penicillin-susceptible laboratory strain R36A causes enrichment of the peptidoglycan in linear muropeptides | Streptococcus pneumoniae |