Inhibitors | Comment | Organism | Structure |
---|---|---|---|
aurothioglucose | complete inhibition at 0.003 mM | Mus musculus | |
Disulfiram | complete inhibition at 0.003 mM | Mus musculus | |
merbromin | - |
Mus musculus | |
Reactive blue 2 | - |
Mus musculus | |
suramin | complete inhibition at 0.001 mM | Mus musculus | |
Tannic acid | complete inhibition at 0.001 mM | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginyl-tRNAArg + bovine serum albumin | - |
Mus musculus | tRNAArg + L-arginyl-[bovine serum albumin] | - |
? | |
L-arginyl-tRNAAsp + beta-actin | - |
Mus musculus | tRNAAsp + L-arginyl-[beta-actin] | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Ate1 | - |
Mus musculus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00028 | - |
in 50 mM HEPES pH 7.5, 25 mM KCl, 15 mM MgCl2, 0.1 mM dithiothreitol, at 37°C | Mus musculus | Tannic acid | |
0.00034 | - |
in 50 mM HEPES pH 7.5, 25 mM KCl, 15 mM MgCl2, 0.1 mM dithiothreitol, at 37°C | Mus musculus | merbromin | |
0.00043 | - |
in 50 mM HEPES pH 7.5, 25 mM KCl, 15 mM MgCl2, 0.1 mM dithiothreitol, at 37°C | Mus musculus | suramin | |
0.00097 | - |
in 50 mM HEPES pH 7.5, 25 mM KCl, 15 mM MgCl2, 0.1 mM dithiothreitol, at 37°C | Mus musculus | Reactive blue 2 |
General Information | Comment | Organism |
---|---|---|
malfunction | impairments of arginyltransferase ATE1 are implicated in congenital heart defects, obesity, cancer, and neurodegeneration | Mus musculus |
physiological function | posttranslational arginylation mediated by arginyltransferase (ATE1) is an emerging major regulator of embryogenesis and cell physiology | Mus musculus |