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Literature summary for 2.3.2.33 extracted from

  • Holland, S.; Scholich, K.
    Regulation of neuronal functions by the E3-ubiquitinligase protein associated with MYC (MYCBP2) (2011), Commun. Integr. Biol., 4, 513-515 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mus musculus Q7TPH6
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Source Tissue

Source Tissue Comment Organism Textmining
neuron
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 Mus musculus
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General Information

General Information Comment Organism
physiological function loss of MYCBP2 in peripheral sensory neurons inhibits the internalization of transient receptor potential vanilloid receptor 1 (TRPV1) in a p38 MAPK-dependent manner. This prevents desensitization of activity-induced calcium increases and prolongs formalin-induced thermal hyperalgesia Mus musculus