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Literature summary for 2.3.1.B42 extracted from

  • Bell, S.D.; Botting, C.H.; Wardleworth, B.N.; Jackson, S.P.; White, M.F.
    The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation (2002), Science, 296, 148-151.
    View publication on PubMed
Search for more literature for 2.3.1.B42

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
27000
-
 x * 27000, SDS-PAGE Saccharolobus solfataricus
50000 60000 gel filtration Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine Saccharolobus solfataricus the enzyme is involved in deacetylating Alba, resulting in an increase in DNA binding affinity of Alba, and thereby repressing transcription nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine Saccharolobus solfataricus P2 the enzyme is involved in deacetylating Alba, resulting in an increase in DNA binding affinity of Alba, and thereby repressing transcription nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97VX5
-
-
Saccharolobus solfataricus P2 Q97VX5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine
-
 Saccharolobus solfataricus nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine the enzyme is involved in deacetylating Alba, resulting in an increase in DNA binding affinity of Alba, and thereby repressing transcription Saccharolobus solfataricus nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine
-
 Saccharolobus solfataricus P2 nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?
NAD+ + [archaeal chromatin protein Alba]-N6-acyl-L-lysine the enzyme is involved in deacetylating Alba, resulting in an increase in DNA binding affinity of Alba, and thereby repressing transcription Saccharolobus solfataricus P2 nicotinamide + [archaeal chromatin protein Alba]-L-lysine + 2'-O-acyl-ADP-ribose
-
 ?

Subunits

Subunits Comment Organism
? x * 27000, SDS-PAGE Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
SSO2478 locus name Saccharolobus solfataricus
ssSir2
-
 Saccharolobus solfataricus