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Literature summary for 2.3.1.97 extracted from

  • Jacquier, M.; Kuriakose, S.; Bhardwaj, A.; Zhang, Y.; Shrivastav, A.; Portet, S.; Varma Shrivastav, S.
    Investigation of novel regulation of N-myristoyltransferase by mammalian target of rapamycin in breast cancer cells (2018), Sci. Rep., 8, 12969 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine upon inhibition of mTOR by treating MCF7 cells with rapamycin, the expression of NMT1 increases with rapamycin treatment over the period of time with a concomitant decrease in mTOR phosphorylation. Activated mammalian target of rapamycin (mTOR) is positively associated with overall survival and recurrence free survival in ER positive breast cancer patients who were later treated with tamoxifen Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P30419 isoform NMT1
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