Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[(diethylamino)methyl]naphthalen-2-ol | - |
Plasmodium vivax | |
2-[(4-methoxybenzyl)amino]-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile | - |
Plasmodium vivax | |
3-butyl-4-(but-3-yn-1-ylsulfanyl)-6-methoxy-2-methylquinoline | - |
Plasmodium vivax | |
3-butyl-6-methoxy-2-methyl-4-[(2-phenylethyl)sulfanyl]quinoline | - |
Plasmodium vivax | |
3-[(2-bromo-3-butyl-6-methoxyquinolin-4-yl)sulfanyl]propanenitrile | - |
Plasmodium vivax | |
3-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propan-1-ol | - |
Plasmodium vivax | |
3-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | - |
Plasmodium vivax | |
3-[(3-butyl-6-methoxyquinolin-4-yl)sulfanyl]propanenitrile | - |
Plasmodium vivax | |
3-[(3-ethyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | - |
Plasmodium vivax | |
3-[(6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | - |
Plasmodium vivax | |
4-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]butanenitrile | - |
Plasmodium vivax | |
6-ethyl-3-(trifluoromethyl)-2,3-dihydro-1,4-benzoxathiine 4,4-dioxide | - |
Plasmodium vivax | |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-(1-hydroxyethyl)quinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-chloroquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-fluoroquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-methylquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)amino]quinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-ethylquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-methylquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-propylquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)sulfanyl]-6-methoxyquinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 4-[(2-cyanoethyl)sulfanyl]quinoline-3-carboxylate | - |
Plasmodium vivax | |
ethyl 6-acetyl-4-(but-3-yn-1-ylsulfanyl)quinoline-3-carboxylate | - |
Plasmodium vivax | |
additional information | NMT inhibitors: screening, synthesis, and structural characterization of their binding mode, overview | Plasmodium vivax | |
[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]acetonitrile | - |
Plasmodium vivax |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00571 | - |
peptide pp60src(2-16) | pH and temperature not specified in the publication | Plasmodium vivax |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Plasmodium vivax | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
myristoyl-CoA + peptide pp60src(2-16) | sequence GSNKSKPKDASQRRR-NH2 | Plasmodium vivax | CoA + N-myristoyl-peptideHs pp60src(2-16) | - |
? |
Synonyms | Comment | Organism |
---|---|---|
N-myristoyltransferase | - |
Plasmodium vivax |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00246 | - |
3-[(3-butyl-6-methoxyquinolin-4-yl)sulfanyl]propanenitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0029 | - |
3-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.00323 | - |
3-[(3-ethyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.00697 | - |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-methylquinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.00777 | - |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-fluoroquinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0109 | - |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-chloroquinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0114 | - |
6-ethyl-3-(trifluoromethyl)-2,3-dihydro-1,4-benzoxathiine 4,4-dioxide | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0116 | - |
3-butyl-4-(but-3-yn-1-ylsulfanyl)-6-methoxy-2-methylquinoline | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0174 | - |
3-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]propan-1-ol | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0216 | - |
3-[(2-bromo-3-butyl-6-methoxyquinolin-4-yl)sulfanyl]propanenitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.02437 | - |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-methylquinoline-3-carboxylate | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.02442 | - |
ethyl 4-[(2-cyanoethyl)sulfanyl]quinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0263 | - |
1-[(diethylamino)methyl]naphthalen-2-ol | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0264 | - |
2-[(4-methoxybenzyl)amino]-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carbonitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0352 | - |
4-[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]butanenitrile | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0424 | - |
ethyl 4-[(2-cyanoethyl)sulfanyl]-6-methoxyquinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.0606 | - |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-ethylquinoline-3-carboxylate | pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
3-[(6-methoxy-2-methylquinolin-4-yl)sulfanyl]propanenitrile | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
ethyl 4-[(2-cyanoethyl)sulfanyl]-2-propylquinoline-3-carboxylate | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
[(3-butyl-6-methoxy-2-methylquinolin-4-yl)sulfanyl]acetonitrile | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
3-butyl-6-methoxy-2-methyl-4-[(2-phenylethyl)sulfanyl]quinoline | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
ethyl 4-[(2-cyanoethyl)amino]quinoline-3-carboxylate | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
ethyl 6-acetyl-4-(but-3-yn-1-ylsulfanyl)quinoline-3-carboxylate | above, pH and temperature not specified in the publication | Plasmodium vivax | |
0.1 | - |
ethyl 4-(but-3-yn-1-ylsulfanyl)-6-(1-hydroxyethyl)quinoline-3-carboxylate | above, pH and temperature not specified in the publication | Plasmodium vivax |