Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-dephospho-CoA | - |
Bos taurus | |
CoA | in absence of KCl, 0.1 mM CoA inhibits activity over 40% irrespective of the concentration of glycine. In presence of KCl, CoA inhibits activity only slightly, less than 10%. In presence of potassium phosphate the inhibition is reduced to less than 2%. 2.5 mM, almost complete inhibition of salt-free enzyme | Bos taurus | |
hippuric acid | competitive with respect to benzoyl-CoA | Bos taurus | |
K+ | K+ is a competitive inhibitor for benzoyl-coenzyme A, not a competitive inhibitor for salicylyl-CoA, K+ increases Km-value for glycine 10fold | Bos taurus | |
Li+ | 110 mM | Bos taurus | |
Mg2+ | - |
Bos taurus | |
Na+ | 110 mM | Bos taurus | |
potassium phosphate | - |
Bos taurus | |
Rb+ | 110 mM | Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2 | - |
glycine | reaction with benzoyl-CoA or salicylyl-CoA | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
34000 | - |
gel filtration | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1 | - |
- |
Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-CoA + glycine | - |
Bos taurus | CoA + N-benzoylglycine | - |
? | |
salicyl-CoA + glycine | - |
Bos taurus | CoA + salicyluric acid | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.03 | - |
hippuric acid | - |
Bos taurus |