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Literature summary for 2.3.1.5 extracted from

  • Dairou, J.; Petit, E.; Ragunathan, N.; Baeza-Squiban, A.; Marano, F.; Dupret, J.M.; Rodrigues-Lima, F.
    Arylamine N-acetyltransferase activity in bronchial epithelial cells and its inhibition by cellular oxidants (2009), Toxicol. Appl. Pharmacol., 236, 366-371.
    View publication on PubMed

Application

Application Comment Organism
medicine exposure of lung epithelial cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the Nat1-dependent cellular biotransformation of aromatic amines Homo sapiens
medicine exposure of lung epithelial cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the Nat2-dependent cellular biotransformation of aromatic amines Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
alveolar cell type II alveolar cell, presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Homo sapiens
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alveolar cell type II alveolar cell, presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Mus musculus
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bronchial epithelial cell presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Homo sapiens
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bronchial epithelial cell presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Mus musculus
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Clara cell presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Homo sapiens
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epithelial cell presence of isoform Nat1. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Homo sapiens
-
epithelial cell presence of isoform Nat2. Exposure of cells to pathophysiologically relevant amounts of oxidants such as H2O2 or peroxyntrite, impairs the cellular biotransformation of aromatic amines Mus musculus
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lung presence of isoform Nat1 Homo sapiens
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lung presence of isoform Nat2 Mus musculus
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