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Literature summary for 2.3.1.302 extracted from
- The biosynthetic pathway of major avenanthramides in oat (2019), Metabolites, 9, 163 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Avena sativa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Avena sativa | A0A4Y5UJ70 | isoform HHT4 | - |
| Avena sativa | Q7XXP3 | isoform HHT1 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| caffeoyl-CoA + 5-hydroxyanthranilate | - |
Avena sativa | avenanthramide C + CoA | - |
? |  |
| additional information | no substrate: feruloyl-CoA | Avena sativa | ? | - |
- |
|
| p-coumaroyl-CoA + 5-hydroxyanthranilate | - |
Avena sativa | avenanthramide A + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HHT1 | - |
Avena sativa |
| HHT4 | - |
Avena sativa |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | oat HHTs are responsible for the biosynthesis of avenanthramide A and avenanthramide C using hydroxyanthranilic acid as an acyl acceptor and p-coumaroyl-CoA and caffeoyl-CoA as an acyl donor, respectively. Contrary, avenanthramide B is synthesized by a caffeoyl-CoA O-methyltransferase enzyme through the methylation of avenanthramide C | Avena sativa |
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Release 2023.1 (January 2023)
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