BRENDA - Enzyme Database show
show all sequences of 2.3.1.26

Cholesterol acyltransferase

Billheimer, J.T.; Methods Enzymol. 111, 286-293 (1985)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
albumin
-
Homo sapiens
albumin
required in the assay medium to prevent the high concentration of oleoly-CoA from inhibiting the enzyme presumably by disrupting the microsomal membrane
Rattus norvegicus
Inhibitors
Inhibitors
Commentary
Organism
Structure
(Z)-17(20)-dehydrocholesterol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
20-Methylcholesterol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
5alpha-dihydroprogesterone
inhibits esterification of endogenous cholesterol
Homo sapiens
acetone
-
Rattus norvegicus
acetone
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
androsterone
inhibits esterification of endogenous cholesterol
Rattus norvegicus
butanol
-
Rattus norvegicus
butanol
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
Cycloartenol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
deoxycorticosterone
inhibits esterification of endogenous cholesterol
Homo sapiens
deoxycorticosterone
-
Rattus norvegicus
Detergents
-
Homo sapiens
Detergents
-
Sus scrofa
Detergents
above their critical micelle concentration, e.g. cholate, deoxycholate, cetyltriethylammonium bromide, Triton X-100, Tween 20, Tween 80, Nonidet P40
Rattus norvegicus
Digitonin
-
Rattus norvegicus
ergosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
ethanol
-
Rattus norvegicus
ethanol
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
Filipin
-
Rattus norvegicus
lanosterol
inhibits esterification of exogenous cholesterol
Helicoverpa zea
lanosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
oleoyl-CoA
inhibits at high concentrations, the inhibition is prevented by serum albumin
Rattus norvegicus
organic solvents
inhibit by perturbing the membrane structure
Rattus norvegicus
Pregn-5-en-3beta-ol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
pregnenolone
inhibits esterification of endogenous cholesterol
Homo sapiens
progesterone
inhibits esterification of endogenous cholesterol reversibly
Homo sapiens
progesterone
inhibits esterification of endogenous cholesterol reversibly
Rattus norvegicus
SC-31769
20-oxa analog of 7-ketosterol
Homo sapiens
SC-31769
20-oxa analog of 7-ketosterol
Rattus norvegicus
sitosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
stanolone
inhibits esterification of endogenous cholesterol
Rattus norvegicus
stigmasterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
testosterone
inhibits esterification of endogenous cholesterol
Homo sapiens
testosterone
-
Rattus norvegicus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Homo sapiens
additional information
-
additional information
use of kinetic parameters such as Km is of limited value due to the physical properties of oleoyl-CoA in solution and the addition of serum albumin to the assay
Rattus norvegicus
0.055
-
oleoyl-CoA
-
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
endoplasmic reticulum
-
Homo sapiens
5783
-
endoplasmic reticulum
-
Rattus norvegicus
5783
-
microsome
-
Saccharomyces cerevisiae
-
-
microsome
-
Sus scrofa
-
-
microsome
-
Homo sapiens
-
-
microsome
-
Rattus norvegicus
-
-
Organic Solvent Stability
Organic Solvent
Commentary
Organism
additional information
the use of organic solvents or strong detergents for the suspension of cholesterol must be avoided because of their affect on the enzyme
Rattus norvegicus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Helicoverpa zea
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-
Saccharomyces cerevisiae
-
-
-
Sus scrofa
-
-
-
Renatured (Commentary)
Commentary
Organism
the enzyme must be reconstituted into an artificial membrane for optimal activity
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Sus scrofa
-
liver
-
Rattus norvegicus
-
liver
-
Homo sapiens
-
peritoneal macrophage
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
assay method
Helicoverpa zea
additional information
-
assay method
Homo sapiens
additional information
-
assay method
Rattus norvegicus
additional information
-
-
Saccharomyces cerevisiae
additional information
-
assay method
Sus scrofa
Storage Stability
Storage Stability
Organism
-80°C, stable for several weeks
Rattus norvegicus
-80°C, stable for several weeks
Saccharomyces cerevisiae
-80°C, stable for several weeks
Helicoverpa zea
ovary, labile to freezing
Rattus norvegicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acyl-CoA + cholesterol
-
486676
Homo sapiens
CoA + cholesterol ester
-
486676
Homo sapiens
?
acyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesterol ester
-
486676
Rattus norvegicus
?
acyl-CoA + cholesterol
-
486676
Sus scrofa
CoA + cholesterol ester
-
486676
Sus scrofa
?
acyl-CoA + cholesterol
-
486676
Saccharomyces cerevisiae
CoA + cholesterol ester
-
486676
Saccharomyces cerevisiae
?
acyl-CoA + cholesterol
-
486676
Helicoverpa zea
CoA + cholesterol ester
-
486676
Helicoverpa zea
?
linoleoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl linoleate
-
486676
Rattus norvegicus
?
additional information
-
486676
Homo sapiens
?
-
-
-
-
additional information
-
486676
Saccharomyces cerevisiae
?
-
-
-
-
additional information
a part of the substrate selectivity may be due to the presence of acyl-CoA hydrolase in the microsomal preparations. For this enzyme, the preferred substrate is palmitoyl-CoA which is hydrolysed about 8times faster than oleoyl-CoA
486676
Rattus norvegicus
?
-
-
-
-
additional information
investigations into the sterol specificity of the enzyme
486676
Rattus norvegicus
?
-
-
-
-
oleoyl-CoA + cholesterol
-
486676
Homo sapiens
CoA + cholesteryl oleate
-
486676
Homo sapiens
?
oleoyl-CoA + cholesterol
-
486676
Sus scrofa
CoA + cholesteryl oleate
-
486676
Sus scrofa
?
oleoyl-CoA + cholesterol
highest activity
486676
Rattus norvegicus
CoA + cholesteryl oleate
-
486676
Rattus norvegicus
?
oleoyl-CoA + cholesterol
highest activity
486676
Saccharomyces cerevisiae
CoA + cholesteryl oleate
-
486676
Saccharomyces cerevisiae
?
oleoyl-CoA + ergosterol
-
486676
Homo sapiens
CoA + ergosteryl oleate
-
-
-
?
oleoyl-CoA + ergosterol
-
486676
Saccharomyces cerevisiae
CoA + ergosteryl oleate
-
486676
Saccharomyces cerevisiae
?
palmitoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl palmitate
-
486676
Rattus norvegicus
?
palmitoyl-CoA + cholesterol
-
486676
Saccharomyces cerevisiae
CoA + cholesteryl palmitate
-
486676
Saccharomyces cerevisiae
?
stearoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl stearate
-
486676
Rattus norvegicus
?
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Helicoverpa zea
37
-
assay at
Homo sapiens
37
-
assay at
Rattus norvegicus
37
-
assay at
Sus scrofa
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
albumin
-
Homo sapiens
albumin
required in the assay medium to prevent the high concentration of oleoly-CoA from inhibiting the enzyme presumably by disrupting the microsomal membrane
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
(Z)-17(20)-dehydrocholesterol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
20-Methylcholesterol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
5alpha-dihydroprogesterone
inhibits esterification of endogenous cholesterol
Homo sapiens
acetone
-
Rattus norvegicus
acetone
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
androsterone
inhibits esterification of endogenous cholesterol
Rattus norvegicus
butanol
-
Rattus norvegicus
butanol
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
Cycloartenol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
deoxycorticosterone
inhibits esterification of endogenous cholesterol
Homo sapiens
deoxycorticosterone
-
Rattus norvegicus
Detergents
-
Homo sapiens
Detergents
-
Sus scrofa
Detergents
above their critical micelle concentration, e.g. cholate, deoxycholate, cetyltriethylammonium bromide, Triton X-100, Tween 20, Tween 80, Nonidet P40
Rattus norvegicus
Digitonin
-
Rattus norvegicus
ergosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
ethanol
-
Rattus norvegicus
ethanol
about 40% inhibition at a final concentration of 1% v/v
Saccharomyces cerevisiae
Filipin
-
Rattus norvegicus
lanosterol
inhibits esterification of exogenous cholesterol
Helicoverpa zea
lanosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
oleoyl-CoA
inhibits at high concentrations, the inhibition is prevented by serum albumin
Rattus norvegicus
organic solvents
inhibit by perturbing the membrane structure
Rattus norvegicus
Pregn-5-en-3beta-ol
inhibits esterification of endogenous cholesterol
Rattus norvegicus
pregnenolone
inhibits esterification of endogenous cholesterol
Homo sapiens
progesterone
inhibits esterification of endogenous cholesterol reversibly
Homo sapiens
progesterone
inhibits esterification of endogenous cholesterol reversibly
Rattus norvegicus
SC-31769
20-oxa analog of 7-ketosterol
Homo sapiens
SC-31769
20-oxa analog of 7-ketosterol
Rattus norvegicus
sitosterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
stanolone
inhibits esterification of endogenous cholesterol
Rattus norvegicus
stigmasterol
inhibits esterification of exogenous cholesterol
Rattus norvegicus
testosterone
inhibits esterification of endogenous cholesterol
Homo sapiens
testosterone
-
Rattus norvegicus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
additional information
-
additional information
-
Homo sapiens
additional information
-
additional information
use of kinetic parameters such as Km is of limited value due to the physical properties of oleoyl-CoA in solution and the addition of serum albumin to the assay
Rattus norvegicus
0.055
-
oleoyl-CoA
-
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
endoplasmic reticulum
-
Homo sapiens
5783
-
endoplasmic reticulum
-
Rattus norvegicus
5783
-
microsome
-
Saccharomyces cerevisiae
-
-
microsome
-
Sus scrofa
-
-
microsome
-
Homo sapiens
-
-
microsome
-
Rattus norvegicus
-
-
Organic Solvent Stability (protein specific)
Organic Solvent
Commentary
Organism
additional information
the use of organic solvents or strong detergents for the suspension of cholesterol must be avoided because of their affect on the enzyme
Rattus norvegicus
Renatured (Commentary) (protein specific)
Commentary
Organism
the enzyme must be reconstituted into an artificial membrane for optimal activity
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Sus scrofa
-
liver
-
Rattus norvegicus
-
liver
-
Homo sapiens
-
peritoneal macrophage
-
Rattus norvegicus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
additional information
-
assay method
Helicoverpa zea
additional information
-
assay method
Homo sapiens
additional information
-
assay method
Rattus norvegicus
additional information
-
-
Saccharomyces cerevisiae
additional information
-
assay method
Sus scrofa
Storage Stability (protein specific)
Storage Stability
Organism
-80°C, stable for several weeks
Rattus norvegicus
-80°C, stable for several weeks
Saccharomyces cerevisiae
-80°C, stable for several weeks
Helicoverpa zea
ovary, labile to freezing
Rattus norvegicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
acyl-CoA + cholesterol
-
486676
Homo sapiens
CoA + cholesterol ester
-
486676
Homo sapiens
?
acyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesterol ester
-
486676
Rattus norvegicus
?
acyl-CoA + cholesterol
-
486676
Sus scrofa
CoA + cholesterol ester
-
486676
Sus scrofa
?
acyl-CoA + cholesterol
-
486676
Saccharomyces cerevisiae
CoA + cholesterol ester
-
486676
Saccharomyces cerevisiae
?
acyl-CoA + cholesterol
-
486676
Helicoverpa zea
CoA + cholesterol ester
-
486676
Helicoverpa zea
?
linoleoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl linoleate
-
486676
Rattus norvegicus
?
additional information
-
486676
Homo sapiens
?
-
-
-
-
additional information
-
486676
Saccharomyces cerevisiae
?
-
-
-
-
additional information
a part of the substrate selectivity may be due to the presence of acyl-CoA hydrolase in the microsomal preparations. For this enzyme, the preferred substrate is palmitoyl-CoA which is hydrolysed about 8times faster than oleoyl-CoA
486676
Rattus norvegicus
?
-
-
-
-
additional information
investigations into the sterol specificity of the enzyme
486676
Rattus norvegicus
?
-
-
-
-
oleoyl-CoA + cholesterol
-
486676
Homo sapiens
CoA + cholesteryl oleate
-
486676
Homo sapiens
?
oleoyl-CoA + cholesterol
-
486676
Sus scrofa
CoA + cholesteryl oleate
-
486676
Sus scrofa
?
oleoyl-CoA + cholesterol
highest activity
486676
Rattus norvegicus
CoA + cholesteryl oleate
-
486676
Rattus norvegicus
?
oleoyl-CoA + cholesterol
highest activity
486676
Saccharomyces cerevisiae
CoA + cholesteryl oleate
-
486676
Saccharomyces cerevisiae
?
oleoyl-CoA + ergosterol
-
486676
Homo sapiens
CoA + ergosteryl oleate
-
-
-
?
oleoyl-CoA + ergosterol
-
486676
Saccharomyces cerevisiae
CoA + ergosteryl oleate
-
486676
Saccharomyces cerevisiae
?
palmitoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl palmitate
-
486676
Rattus norvegicus
?
palmitoyl-CoA + cholesterol
-
486676
Saccharomyces cerevisiae
CoA + cholesteryl palmitate
-
486676
Saccharomyces cerevisiae
?
stearoyl-CoA + cholesterol
-
486676
Rattus norvegicus
CoA + cholesteryl stearate
-
486676
Rattus norvegicus
?
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
37
-
assay at
Helicoverpa zea
37
-
assay at
Homo sapiens
37
-
assay at
Rattus norvegicus
37
-
assay at
Sus scrofa
Other publictions for EC 2.3.1.26
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
736719
Warrier
Sterol O-acyltransferase 2-dri ...
Mus musculus
Lipids
51
151-157
2016
-
1
-
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
3
3
-
-
-
736178
He
Functional characterization of ...
Homo sapiens
Gene
566
236-241
2015
-
1
1
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
2
-
-
-
736702
Rogers
Acyl-CoA:cholesterol acyltrans ...
Homo sapiens, Mus musculus
J. Steroid Biochem. Mol. Biol.
151
102-107
2015
6
-
2
-
-
-
-
2
4
-
4
4
-
7
-
-
1
-
-
12
-
-
14
3
-
-
-
-
-
-
-
-
-
-
-
12
-
3
-
-
-
-
-
-
-
4
4
-
4
4
-
-
-
1
-
14
-
-
14
3
-
-
-
-
-
-
-
-
-
8
14
-
-
-
736937
Zhan
Design and synthesis of simple ...
Homo sapiens
Org. Biomol. Chem.
14
747-751
2015
-
1
-
-
-
-
7
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
10
-
1
-
-
-
-
-
10
7
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
735970
Zhang
Cholesterol esters (CE) derive ...
Mus musculus
Circ. Res.
115
826-833
2014
-
-
-
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
2
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
736580
Tomita
Acyl-CoA:cholesterol acyltrans ...
Homo sapiens, Mus musculus, Mus musculus C57BL/6
J. Hepatol.
61
98-106
2014
-
2
-
-
-
-
-
-
-
-
-
6
-
3
-
-
-
-
-
9
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
9
-
-
6
-
-
-
-
-
-
-
-
-
-
4
4
-
-
-
735753
Ohtawa
Synthesis and structure-activi ...
Homo sapiens
Bioorg. Med. Chem. Lett.
23
1285-1287
2013
-
-
-
-
-
-
45
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
88
-
-
-
-
-
-
-
88
90
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
735754
Ohtawa
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Purification of recombinant ac ...
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Novel tetrahydroisoquinoline d ...
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AM-251 and SR144528 are acyl C ...
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Novel 1,4-diarylpiperidine-4-m ...
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Asano
Synthesis and structure-activi ...
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Synthesis of a novel series of ...
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Xin
Study of the insulin signaling ...
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Ohshiro
The selectivity of beauverioli ...
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A novel technical approach for ...
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2009
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706575
Antalis
Docosahexaenoic acid is a subs ...
Homo sapiens
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2009
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Heterocyclic compounds from Ch ...
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Parini
Cholesterol synthesis inhibiti ...
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2008
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3
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Lee
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Human acyl-CoA:cholesterol acy ...
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3
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Hans
Differential effects of PARP i ...
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686600
An
Inhibition of acyl-coenzyme A: ...
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407-417
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Identification of the interact ...
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21
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6
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Identification of putative act ...
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4
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2
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Novel indoline-based acyl-CoA: ...
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J. Med. Chem.
51
4823-4833
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2
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1
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1
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4
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4
1
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1
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1
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1
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4
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2
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1
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1
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688767
Miike
Effects of an anti-oxidative A ...
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Life Sci.
82
79-84
2008
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1
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1
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2
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1
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1
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1
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701988
Lam
Conjugated and non-conjugated ...
Mesocricetus auratus
Atherosclerosis
198
85-93
2008
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2
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2
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-
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703975
Kanome
Angiotensin II upregulates acy ...
Homo sapiens
Hypertens. Res.
31
1801-1810
2008
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2
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2
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1
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Ohshiro
Selectivity of pyripyropene de ...
Chlorocebus aethiops
J. Antibiot.
61
503-508
2008
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1
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18
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Sakai
Selective inhibition of acyl-C ...
Chlorocebus aethiops
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568-572
2008
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9
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9
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705083
Choi
Penicillium griseofulvum F1959 ...
Rattus norvegicus
J. Microbiol. Biotechnol.
18
1663-1665
2008
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1
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1
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1
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-
-
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-
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706580
Locke
Androgen-mediated cholesterol ...
Homo sapiens
Prostate
68
20-33
2008
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-
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1
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672494
Park
Human acyl-CoA: cholesterol ac ...
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30
205-207
2007
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1
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-
5
-
-
-
-
1
-
5
-
-
1
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
8
-
-
1
-
-
-
-
12
11
-
-
-
-
-
1
-
-
-
1
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
672617
Benfatti
Synthesis and biological evalu ...
Mammalia, Oryctolagus cuniculus
Bioorg. Med. Chem. Lett.
17
1946-1950
2007
-
1
-
-
-
-
14
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
8
-
1
-
-
-
-
-
8
14
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674216
Ohshiro
Selectivity of microbial acyl- ...
Chlorocebus aethiops, Cricetulus griseus, Mus musculus, Rattus norvegicus
J. Antibiot.
60
43-51
2007
-
-
-
-
-
-
53
-
7
-
-
3
-
4
-
-
2
-
-
3
-
-
3
-
2
-
-
-
-
-
-
-
-
-
113
-
-
-
-
-
-
-
113
53
-
-
7
-
-
3
-
-
-
2
-
3
-
-
3
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
684780
Fujiwara
Esculeogenin A, a new tomato s ...
Homo sapiens, Mus musculus
Arterioscler. Thromb. Vasc. Biol.
27
2400-2406
2007
-
2
-
-
-
-
5
-
2
-
-
2
-
7
-
-
1
-
-
4
5
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
5
-
-
2
-
-
2
-
-
-
1
-
4
5
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
684799
Terasaka
ACAT inhibitor pactimibe sulfa ...
Homo sapiens, Mus musculus, Rattus norvegicus
Atherosclerosis
190
239-247
2007
-
1
1
-
-
-
9
-
-
-
-
3
-
4
-
-
2
-
-
3
-
-
6
-
2
-
-
-
2
-
-
-
-
-
10
-
1
1
-
-
-
-
10
9
-
-
-
-
-
3
-
-
-
2
-
3
-
-
6
-
2
-
-
-
2
-
-
-
-
-
-
-
-
-
684800
Ikenoya
A selective ACAT-1 inhibitor, ...
Homo sapiens
Atherosclerosis
191
290-297
2007
-
1
1
-
-
-
2
2
1
-
1
1
-
4
-
-
1
-
-
3
-
-
2
-
1
-
-
-
1
-
-
-
1
-
5
-
1
1
-
-
-
-
5
2
1
2
1
-
1
1
-
-
-
1
-
3
-
-
2
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
684882
Pramfalk
Cholesterol regulates ACAT2 ge ...
Homo sapiens
Biochem. Biophys. Res. Commun.
364
402-409
2007
1
-
-
-
-
-
-
-
2
-
-
1
-
3
-
-
1
-
-
6
20
-
1
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
1
-
6
20
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
685566
An
Human ACAT inhibitory effects ...
Homo sapiens
Bioorg. Med. Chem. Lett.
17
1112-1116
2007
-
1
1
-
-
-
11
-
-
-
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1
-
3
-
-
-
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-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
19
-
1
1
-
-
-
-
19
11
-
-
-
-
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1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
685611
Kitamura
The new acyl-CoA cholesterol a ...
Homo sapiens
Biopharm. Drug Dispos.
28
517-525
2007
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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1
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-
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-
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1
-
-
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-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686560
Adameova
The myocardial infarct size-li ...
Rattus norvegicus
Eur. J. Pharmacol.
576
114-121
2007
-
1
-
-
-
-
1
-
1
-
-
1
-
3
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
686931
Vojtassakova
Effect of VULM 1457, an ACAT i ...
Mesocricetus auratus
Gen. Physiol. Biophys.
26
254-259
2007
-
1
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688060
Choi
Glabrol, an acyl-coenzyme A: c ...
Homo sapiens, Rattus norvegicus
J. Ethnopharmacol.
110
563-566
2007
-
2
-
-
-
-
2
-
1
-
-
2
-
4
-
-
-
-
-
2
-
-
4
-
2
-
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
2
2
-
-
1
-
-
2
-
-
-
-
-
2
-
-
4
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
688139
He
Effect of tumor necrosis facto ...
Homo sapiens
J. Huazhong Univ. Sci. Technol. Med. Sci.
27
170-172
2007
1
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
7
-
2
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
7
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
689426
Rho
ACAT inhibition of alkamides i ...
Homo sapiens, Rattus norvegicus
Phytochemistry
68
899-903
2007
-
-
-
-
-
-
12
-
1
-
-
2
-
2
-
-
1
-
-
2
-
-
4
-
1
-
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
6
12
-
-
1
-
-
2
-
-
-
1
-
2
-
-
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
671655
Gelain
3-Heptylamino-5-phenylpyridazi ...
Rattus norvegicus
Arch. Pharm.
339
645-651
2006
-
-
-
-
-
-
17
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
17
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671658
Im
Acyl-CoA: cholesterol acyltran ...
Homo sapiens
Arch. Pharm. Res.
29
191-194
2006
-
-
-
-
-
-
2
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
2
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671668
Bell
Liver-specific inhibition of a ...
Mus musculus
Arterioscler. Thromb. Vasc. Biol.
26
1814-1820
2006
-
1
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671677
Suguro
Serotonin acts as an up-regula ...
Homo sapiens
Atherosclerosis
186
275-281
2006
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
671850
Song
Human acyl-CoA:cholesterol acy ...
Homo sapiens
Biochem. J.
394
617-626
2006
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672602
Ban
Synthesis and biological activ ...
Rattus norvegicus
Bioorg. Med. Chem. Lett.
16
44-48
2006
-
-
-
-
-
-
10
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
-
-
-
10
10
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673648
An
A critical role for the histid ...
Homo sapiens
FEBS Lett.
580
2741-2749
2006
-
-
1
-
7
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
674996
Zamorano-Leon
Direct effect of F12511, a sys ...
Bos taurus
J. Cardiovasc. Pharmacol.
48
128-134
2006
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
1
-
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-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660837
Kim
Triterpenoids from the flower ...
Homo sapiens
Arch. Pharm. Res.
28
550-556
2005
-
-
-
-
-
-
7
-
-
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
661010
Liu
Investigating the allosterism ...
Homo sapiens
Biochem. J.
391
389-397
2005
1
-
-
-
-
-
-
-
-
-
-
-
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3
-
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-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672028
Guo
The disulfide linkage and the ...
Homo sapiens
Biochemistry
44
6537-6546
2005
-
-
1
-
-
-
-
-
1
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
672577
Jeong
Saucerneol B derivatives as hu ...
Homo sapiens
Bioorg. Med. Chem. Lett.
15
385-388
2005
-
-
-
-
-
-
10
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
8
20
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
673109
Kharbanda
Systemic Acyl-CoA:cholesterol ...
Homo sapiens
Circulation
111
804-807
2005
-
1
-
-
-
-
-
-
-
-
-
-
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3
-
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-
-
-
-
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-
-
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-
-
1
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-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675261
Freeman
Acyl-coenzyme A:cholesterol ac ...
Mus musculus
J. Lipid Res.
46
1933-1943
2005
-
-
-
-
-
-
-
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-
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2
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-
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1
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-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675290
Gelain
Mono- or diphenylpyridazines c ...
Rattus norvegicus
J. Med. Chem.
48
7708-7713
2005
-
-
-
-
-
-
13
-
1
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-
-
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2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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-
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-
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-
-
-
-
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-
13
-
-
1
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-
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
675771
Bose
Age-related alteration in hepa ...
Mus musculus, Mus musculus C57/BL6
Mech. Ageing Dev.
126
740-751
2005
-
-
-
-
-
-
-
-
1
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-
-
-
11
-
-
-
-
-
1
-
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-
-
-
-
-
-
-
-
-
-
-
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-
-
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-
-
-
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-
1
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-
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-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
660876
Kim
Molecular cloning and biochemi ...
Candida albicans
Biochem. Biophys. Res. Commun.
319
911-919
2004
-
-
1
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4
1
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2
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4
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3
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1
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Dietary fatty acids regulate a ...
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662765
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4
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Human acyl-coenzyme A:choleste ...
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5
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2
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Mutant acyl-coenzyme A: choles ...
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18
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1
1
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1
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18
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3
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1
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1
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1
1
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486710
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Role of the N-terminal hydroph ...
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1
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1
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1
2
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486708
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Differential expression of ACA ...
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15
4
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3
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1
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486707
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-
Activities of acyl-CoA:cholest ...
Alligator mississippiensis
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1
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486704
Matsuda
Molecular cloning, functional ...
Rattus norvegicus
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1998
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4
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1
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4
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1
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1
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486705
Khelef
Immunolocalization of acyl-coe ...
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273
11218-11224
1998
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3
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3
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1
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Identification of a form of ac ...
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17
5
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3
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1
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4
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3
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2
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17
5
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3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
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486701
Bhuvaneswaran
Activation of acyl-CoA:cholest ...
Rattus norvegicus, Rattus norvegicus male Wistar
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27-34
1997
1
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7
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2
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2
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1
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2
2
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2
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-
-
-
-
-
-
-
-
-
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-
-
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486702
Kerkhoff
Acyl-CoA binding protein (ACBP ...
Homo sapiens
Biochim. Biophys. Acta
1346
163-172
1997
1
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3
2
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2
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1
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1
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3
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1
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2
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486703
Chang
Acyl-coenzyme A:cholesterol ac ...
Cavia porcellus, Columba sp., Cricetulus griseus, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Platyrrhini, Rattus norvegicus, Sus scrofa
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15
1
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2
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13
4
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14
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2
9
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1
2
41
9
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9
1
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Cloning and expression in Xeno ...
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Molecular cloning and characte ...
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1996
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2
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2
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Activation of acyl-coenzyme A: ...
Homo sapiens
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4
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3
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1
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1
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1
1
1
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Uelmen
Tissue-specific expression and ...
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1
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13
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Becker
Purification, cloning, and exp ...
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1
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2
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2
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1
1
5
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4
1
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Molecular cloning and function ...
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2
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1
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1
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1
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1
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-
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2
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-
1
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-
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486678
Tabas
Rabbit and human liver contain ...
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5
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-
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3
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3
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3
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-
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4
-
-
5
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-
-
-
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486692
Einarsson
Studies on acyl-coenzyme A:cho ...
Homo sapiens
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1989
1
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1
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1
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1
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-
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2
1
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-
-
-
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486683
Kinnunen
Chemical modification of acyl- ...
Oryctolagus cuniculus
Biochemistry
27
7344-7350
1988
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5
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1
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14
1
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2
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4
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5
4
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1
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14
1
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2
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-
-
-
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Cadigan
A simple method for reconstitu ...
Cricetulus griseus, Homo sapiens
J. Lipid Res.
29
1683-1692
1988
2
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4
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2
8
2
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-
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-
-
-
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2
-
-
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-
-
-
-
-
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-
-
-
-
-
-
-
-
2
8
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486680
Miller
5alpha-Cholest-8(14)-en-3beta- ...
Rattus norvegicus, Rattus norvegicus male Sprague-Dawley
Biochem. Biophys. Res. Commun.
148
934-940
1987
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1
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1
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4
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-
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3
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8
-
-
-
-
-
-
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-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
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-
-
-
-
-
-
-
3
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486687
Marco
Acyl coenzyme A:cholesterol ac ...
Gallus gallus
Biochim. Biophys. Acta
875
599-604
1986
1
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1
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1
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1
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1
2
1
2
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1
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1
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1
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1
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1
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1
2
1
2
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1
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-
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1
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-
-
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-
-
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486676
Billheimer
Cholesterol acyltransferase ...
Helicoverpa zea, Homo sapiens, Rattus norvegicus, Saccharomyces cerevisiae, Sus scrofa
Methods Enzymol.
111
286-293
1985
2
-
-
-
-
-
34
3
6
-
-
-
1
5
-
-
-
-
1
4
5
4
19
-
4
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
34
-
3
6
-
-
-
1
-
-
-
1
4
5
4
19
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
486694
Kwok
Inactivation of acyl-CoA:chole ...
Rattus norvegicus
Biochem. Int.
8
271-282
1984
-
-
-
-
-
-
4
-
-
1
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486677
Chang
-
Acyl coenzyme A:cholesterol O- ...
Cavia porcellus, Columba sp., Cricetulus griseus, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Platyrrhini, Rattus norvegicus, Sus scrofa
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
16
523-539
1983
15
-
-
-
-
-
25
2
9
-
-
18
-
9
-
-
1
-
3
32
11
3
48
-
9
-
1
-
-
-
-
-
2
-
-
15
-
-
-
-
-
-
-
25
2
2
9
-
-
18
-
-
-
1
3
32
11
3
48
-
9
-
1
-
-
-
-
-
-
-
-
-
-
-
486689
Suckling
In vitro regulation of bovine ...
Bos taurus, Rattus norvegicus
Biochim. Biophys. Acta
753
422-429
1983
4
-
-
-
-
-
2
-
2
3
-
-
-
4
-
-
-
-
-
7
7
-
4
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
2
-
-
2
3
-
-
-
-
-
-
-
7
7
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486681
Tavani
The sterol substrate specifici ...
Rattus norvegicus, Rattus norvegicus male Sprague-Dawley
J. Lipid Res.
23
774-781
1982
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
19
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
19
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486682
Doolittle
Solubilization, partial purifi ...
Sus scrofa
Biochemistry
21
674-679
1982
1
-
-
-
-
-
2
-
1
-
-
-
-
3
-
-
1
-
1
2
2
1
1
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
1
2
2
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486690
Doolittle
Acyl-CoA:cholesterol acyltrans ...
Cricetulus griseus
Biochim. Biophys. Acta
713
529-537
1982
1
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
1
3
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
3
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486684
Helgerud
Acyl-CoA:cholesterol acyltrans ...
Homo sapiens
J. Lipid Res.
22
271-277
1981
1
-
-
-
-
-
-
1
1
-
-
1
-
2
-
-
-
-
-
6
4
2
3
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
1
-
-
1
-
-
-
-
-
6
4
2
3
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
486679
Simpson
Acyl CoA:cholesterol acyl tran ...
Homo sapiens
Arch. Biochem. Biophys.
200
79-85
1980
2
-
-
-
-
-
10
1
1
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
2
-
-
1
-
-
-
-
10
-
1
1
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486685
Erickson
Rat liver acyl-coenzyme A:chol ...
Rattus norvegicus, Rattus norvegicus male Sprague-Dawley
J. Lipid Res.
21
930-941
1980
4
-
-
-
-
-
10
-
4
-
-
2
1
5
-
-
-
-
-
2
1
1
6
-
1
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
10
-
-
4
-
-
2
1
-
-
-
-
2
1
1
6
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
486688
Brecher
Properties of acyl-CoA:cholest ...
Oryctolagus cuniculus, Rattus norvegicus
Biochim. Biophys. Acta
617
458-471
1980
4
-
-
-
-
-
1
-
2
-
-
-
-
4
-
-
-
-
-
7
3
-
4
-
2
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
7
3
-
4
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
486675
Taketani
Characterization of sterol-est ...
Saccharomyces cerevisiae
Biochim. Biophys. Acta
575
148-155
1979
-
-
-
-
-
-
3
2
2
-
-
-
-
2
-
-
-
-
-
-
1
-
13
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
3
-
2
2
-
-
-
-
-
-
-
-
-
1
-
13
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486686
Balasubramaniam
The submicrosomal localization ...
Rattus norvegicus, Rattus norvegicus male Wistar
Biochem. J.
174
863-872
1978
-
-
-
-
-
-
1
-
1
-
-
-
-
6
-
-
-
-
-
1
2
-
4
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
2
-
4
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
486691
Kaduce
Acylcoenzyme A:cholesterol acy ...
Mus musculus
Biochem. Biophys. Res. Commun.
81
462-468
1978
-
-
-
-
-
-
-
1
1
-
-
-
-
1
-
-
-
-
1
2
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
2
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
486674
Sgoutas
Effect of geometry and positio ...
Rattus norvegicus
Biochemistry
9
1826-1833
1970
-
-
-
-
-
-
-
3
1
1
-
-
-
1
-
-
-
-
-
1
-
-
7
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
3
1
1
-
-
-
-
-
-
-
1
-
-
7
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-