Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of a DELTArrmJ deletion strain | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + uridine2552 in 23S rRNA | Escherichia coli | rrmJ gene encodes a methyltransferase that modifies the U2552 residue of 23S rRNA | S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA | - |
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Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
gene rrmJ | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + uridine2552 in 23S rRNA | - |
Escherichia coli | S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA | - |
? | |
S-adenosyl-L-methionine + uridine2552 in 23S rRNA | rrmJ gene encodes a methyltransferase that modifies the U2552 residue of 23S rRNA | Escherichia coli | S-adenosyl-L-homocysteine + 2'-O-methyluridine2552 in 23S rRNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RrmJ | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
S-adenosyl-L-methionine | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | rrmJ gene deletion causes a severe growth defect and accumulation of aberrant 50S ribosomal subunits in DELTArrmJ. Overexpression of GTPase Der suppresses growth impairment, effects of several Der mutants, overview. In a rrmJ deletion strain, two GTPase domains of Der regulate its association with 50S subunit via the KH-like domain. Phenotypes, overview | Escherichia coli |