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Literature summary for 1.8.1.9 extracted from

  • Holmgren, A.; Lyckeborg, C.
    Enzymatic reduction of alloxan by thioredoxin and NADPH-thioredoxin reductase (1980), Proc. Natl. Acad. Sci. USA, 77, 5149-5152.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.1.9

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.07
-
 thioredoxin
-
 Bos taurus
0.33
-
 thioredoxin
-
 Bos taurus
0.33
-
 alloxan
-
 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000
-
 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
thymus
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alloxan + NADPH
-
 Bos taurus ?
-
 ?
thioredoxin + NADP+
-
 Bos taurus thioredoxin disulfide + NADPH
-
 ir
thioredoxin + NADP+
-
 Bos taurus thioredoxin disulfide + NADPH + H+
-
 r

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Bos taurus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
167
-
 alloxan
-
 Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
 assay at Bos taurus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Bos taurus