Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N,N'-dicyclohexylcarbodiimide | 0.3 mM significantly inhibits the the energy-linked NADH-NADP+ reactions, but not the nonenergy-linked NADH-NADP+ transhydrogenation | Manduca sexta | |
rotenone | with rotenone addition, the NADH-NADP+ activity is inhibited significantly and the remaining activity reflects the nonenergy-linked reaction | Manduca sexta |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | - |
Manduca sexta | 31966 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Manduca sexta | - |
tobacco hornworm | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
midgut | - |
Manduca sexta | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADP+ + NADH | - |
Manduca sexta | NADPH + NAD+ | - |
r | |
NADPH + 3-acetylpyridine-NAD(P)+ | - |
Manduca sexta | NADP+ + 3-acetylpyridine-NAD(P)H | - |
r |
Synonyms | Comment | Organism |
---|---|---|
mitochondrial transhydrogenase | - |
Manduca sexta |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Manduca sexta |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
4 | 6 | activity decreases as the pH approaches 6.0, although a second minor peak is evident at pH 5.0, the activity of the nonenergy-linked reaction decreases with medium acidification and activity loss is most notable at pH 4.0 | Manduca sexta |