Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | activity is maximal when FAD, phenazine ethosulfate and glycerol are included in the assay | Oryctolagus cuniculus |
Application | Comment | Organism |
---|---|---|
medicine | L-pipecolic oxidase activity is deficient in patients with peroxisome biogenesis disorders | Oryctolagus cuniculus |
medicine | L-pipecolic oxidase activity is deficient in patients with peroxisome biogenesis disorders | Macacine alphaherpesvirus 1 |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antimycin A | - |
Oryctolagus cuniculus | |
L-proline | - |
Oryctolagus cuniculus | |
phenazine ethosulfate | - |
Macacine alphaherpesvirus 1 | |
rotenone | - |
Oryctolagus cuniculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.74 | - |
L-pipecolic acid | - |
Oryctolagus cuniculus | |
4.2 | - |
L-pipecolic acid | - |
Macacine alphaherpesvirus 1 |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | soluble fraction | Oryctolagus cuniculus | 5739 | - |
peroxisome | membrane-associated | Macacine alphaherpesvirus 1 | 5777 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-pipecolate + O2 | Oryctolagus cuniculus | - |
2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? | |
L-pipecolate + O2 | Macacine alphaherpesvirus 1 | - |
2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Macacine alphaherpesvirus 1 | - |
cynomolgus monkey | - |
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Oryctolagus cuniculus | - |
heart | - |
Oryctolagus cuniculus | - |
kidney | highest activity in the kidney cortex | Oryctolagus cuniculus | - |
kidney | highest activity in the kidney cortex | Macacine alphaherpesvirus 1 | - |
liver | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-pipecolate + O2 | - |
Oryctolagus cuniculus | 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | - |
? | |
L-pipecolate + O2 | - |
Macacine alphaherpesvirus 1 | 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | - |
? | |
L-pipecolate + O2 | - |
Oryctolagus cuniculus | 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? | |
L-pipecolate + O2 | - |
Macacine alphaherpesvirus 1 | 2,3,4,5-tetrahydropyridine-2-carboxylate + H2O2 | the product reacts with water to form 2-aminoadipate 6-semialdehyde | ? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | - |
- |
Macacine alphaherpesvirus 1 |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Oryctolagus cuniculus | |
FAD | - |
Macacine alphaherpesvirus 1 |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
10 | - |
L-proline | - |
Oryctolagus cuniculus |