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Literature summary for 1.4.3.4 extracted from

  • Cheng, K.; Li, S.; Lv, X.; Tian, Y.; Kong, H.; Huang, X.; Duan, Y.; Han, J.; Xie, Z.; Liao, C.
    Design, synthesis and biological evaluation of novel human monoamine oxidase B inhibitors based on a fragment in an X-ray crystal structure (2019), Bioorg. Med. Chem. Lett., 29, 1012-1018 .
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
clorgiline
-
 Homo sapiens
Clorgyline
-
 Homo sapiens
isatin
-
 Homo sapiens
safinamide
-
 Homo sapiens
selegiline
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P21397
-
-
Homo sapiens P27338
-
-

Synonyms

Synonyms Comment Organism
monoamine oxidase A
-
 Homo sapiens
monoamine oxidase B
-
 Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.033
-
 pH and temperature not specified in the publication Homo sapiens selegiline
0.038
-
 pH and temperature not specified in the publication Homo sapiens clorgiline
0.039
-
 pH and temperature not specified in the publication Homo sapiens safinamide
20.27
-
 pH and temperature not specified in the publication Homo sapiens Clorgyline
54.35
-
 pH and temperature not specified in the publication Homo sapiens selegiline
223.5
-
 pH and temperature not specified in the publication Homo sapiens safinamide
368.4
-
 pH and temperature not specified in the publication Homo sapiens isatin