KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
tetrahydrofolate | pH 8.0, 37°C | Gallus gallus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
sedimentation equilibrium centrifugation, component T-protein | Gallus gallus |
38000 | - |
gel filtration, component T-protein | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | P28337 | i.e. aminomethyltransferase component T-protein, cf. EC 2.1.2.10 | - |
Purification (Comment) | Organism |
---|---|
isolation of component T-protein | Gallus gallus |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycine + tetrahydrofolate + NAD+ | - |
Gallus gallus | 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
multimer | x * 41000, SDS-PAGE, component T-protein | Gallus gallus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Gallus gallus | |
tetrahydrofolate | - |
Gallus gallus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Gallus gallus | component T-protein | - |
9.8 |
General Information | Comment | Organism |
---|---|---|
physiological function | the component T-protein catalyzes the degradation of the protein-bound intermediate (-CH2NH2 moiety of glycine) to a 1-carbon unit and NH3. The reaction is dependent on tetrahydrofolate. T-protein associates with H-protein forming a complex of one molecule each of T-protein and H-protein | Gallus gallus |