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Literature summary for 1.4.1.2 extracted from

  • Han, T.; Cannon, R.; Gallo, S.; Villas-Boas, S.
    A metabolomic study of the effect of Candida albicans glutamate dehydrogenase deletion on growth and morphogenesis (2019), NPJ Biofilms Microbiomes, 5, 13 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Candida albicans A0A1D8PI00 isoform GDH2
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Candida albicans ATCC MYA-2876 A0A1D8PI00 isoform GDH2
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Synonyms

Synonyms Comment Organism
GDH2
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Candida albicans

General Information

General Information Comment Organism
physiological function the gdh2/gdh2 mutant is unable to grow on either arginine or proline as a sole carbon and nitrogen source. There is no obvious difference in hyphal development between the wild-type (parental) and the mutant strains when cultured in minimum mineral medium or under other hyphae-inducing conditions. When the gdh2/gdh2 mutant utilizes glucose as the sole carbon source, most of the intracellular metabolites are found at lower concentrations than in the wild-type strain except for cysteine, malonate, nicotinate, 9-heptadecenoate, and 2-phosphoenolpyruvate Candida albicans