Literature summary for 1.4.1.2 extracted from

Dong, J.; Kan, B.; Liu, H.; Zhan, M.; Wang, S.; Xu, G.; Han, R.; Ni, Y.
CRISPR-Cpf1-assisted engineering of Corynebacterium glutamicum SNK118 for enhanced L-ornithine production by NADP-dependent glyceraldehyde-3-phosphate dehydrogenase and NADH-dependent glutamate dehydrogenase (2020), Appl. Biochem. Biotechnol., 191, 955-967 .

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Application

Application	Comment	Organism
synthesis	produktion of L-ornithine in Corynebacterium glutamicum SNK118, by deletion of genes argF, argR, and ncgl2228 to block the degradation of L-ornithine, and overexpression of NADP-dependent glyceraldehyde 3-phosphate dehydrogenases gene from Clostridium saccharobutylicum and glutamate dehydrogenase RocG. In fed-batch fermentation, L-ornithine of 88.26 g/l with productivity of 1.23 g/l/h (over 72 h) and yield of 0.414 g/g glucose are achieved by the final strain in a 10-l bioreactor	Bacillus subtilis

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	-	-	-
Bacillus subtilis HB-1	-	-	-

Synonyms

Synonyms	Comment	Organism
RocG	-	Bacillus subtilis

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Release 2023.1 (January 2023)