General Stability | Organism |
---|---|
UVB irradiation does not affect enzyme activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
25-hydroxyvitamin D3 | - |
Homo sapiens | |
cyclopamine | treatment of adult human epidermal keratinocytes with 0.01 mM cyclopamine results in a decrease in enzyme activity (50% of control activity at 3 h) | Homo sapiens | |
additional information | not inhibited by 1alpha,25-dihydroxyvitamin D3 and vitamin D3 | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + NADP+ | Homo sapiens | - |
cholesta-5,7-dien-3beta-ol + NADPH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HaCaT cell | - |
Homo sapiens | - |
HEKa cell | human epidermal keratinocyte | Homo sapiens | - |
Hep-G2 cell | - |
Homo sapiens | - |
hepatoma cell | - |
Homo sapiens | - |
keratinocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + NADP+ | - |
Homo sapiens | cholesta-5,7-dien-3beta-ol + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Dhcr7 | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Homo sapiens |