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Literature summary for 1.3.1.124 extracted from

  • Kimura, C.; Kondo, A.; Koeda, N.; Yamanaka, H.; Mizugaki, M.
    Studies on the metabolism of unsaturated fatty acids. XV. Purification and properties of 2,4-dienoyl-CoA reductase from rat liver peroxisomes (1984), J. Biochem., 96, 1463-1469 .
    View publication on PubMed
Search for more literature for 1.3.1.124

Activating Compound

Activating Compound Comment Organism Structure
BSA activation, optimum concentration 0.5-1 mg/ml Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0154
-
 (2E,4E)-2,4-decadienoyl-CoA pH 7.4, 25°C Rattus norvegicus
0.0158
-
 (2E,4E)-2,4-octadienoyl-CoA pH 7.4, 25°C Rattus norvegicus
0.032
-
 NADPH pH 7.4, 25°C Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
 Rattus norvegicus 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
120000
-
 gel filtration Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9Z2M4 isoform Decr2
-

Purification (Commentary)

Purification (Comment) Organism
purification and separation of the peroxisomal and mitochondrial 2,4-dienoyl-CoA reductases Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2E,4E)-2,4-decadienoyl-CoA + NADPH + H+
-
 Rattus norvegicus (3E)-3-decaenoyl-CoA + NADP+
-
 ?
(2E,4E)-2,4-octadienoyl-CoA + NADPH + H+
-
 Rattus norvegicus (3E)-3-octaenoyl-CoA + NADP+
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 33000, SDS-PAGE Rattus norvegicus