Literature summary for 1.3.1.124 extracted from

Gurvitz, A.; Wabnegger, L.; Yagi, A.I.; Binder, M.; Hartig, A.; Ruis, H.; Hamilton, B.; Dawes, I.W.; Hiltunen, J.K.; Rottensteiner, H.
Function of human mitochondrial 2,4-dienoyl-CoA reductase and rat monofunctional Delta3-Delta2-enoyl-CoA isomerase in beta-oxidation of unsaturated fatty acids (1999), Biochem. J., 344 Pt 3, 903-914 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Homo sapiens	5739	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q16698	-	-

Synonyms

Synonyms	Comment	Organism
DECR	-	Homo sapiens
DECR1	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	human mitochondrial 2,4-reductase functions in the beta-oxidation of unsaturated fatty acids. A yeast sps19D mutant expressing human 2,4-reductase ending with the native C-terminus cannot grow on petroselinic acid medium but can grow when the protein is extended with a peroxisomal targeting tripeptide, Ser-Lys-Leu	Homo sapiens

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Release 2023.1 (January 2023)