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Literature summary for 1.3.1.118 extracted from

  • Jain, S.; Sharma, S.; Sen, D.; Pandya, S.
    Enoyl-acyl carrier protein reductase (INHA) A remarkable target to exterminate tuberculosis (2021), Anti-Infect. Agents, 19, 252-266 .
No PubMed abstract available
Search for more literature for 1.3.1.118

Inhibitors

Inhibitors Comment Organism Structure
9H-fluoren-9-yl-piperazine
-
 Mycobacterium tuberculosis
triclosan
-
 Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis
-
-
-
Mycobacterium tuberculosis H37Rv
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trans-2-dodecenoyl-CoA + NADH + H+
-
 Mycobacterium tuberculosis dodecanoyl-CoA + NAD+
-
 ?
trans-2-dodecenoyl-CoA + NADH + H+
-
 Mycobacterium tuberculosis H37Rv dodecanoyl-CoA + NAD+
-
 ?

Synonyms

Synonyms Comment Organism
2-trans-enoyl-ACP reductase
-
 Mycobacterium tuberculosis
InhA
-
 Mycobacterium tuberculosis

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Mycobacterium tuberculosis