Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.1.3 extracted from

  • Jelski, W.; Szmitkowski, M.
    Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in the cancer diseases (2008), Clin. Chim. Acta, 395, 1-5.
    View publication on PubMed
Search for more literature for 1.2.1.3

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol ALDH I Homo sapiens 5829
-
mitochondrion ALDH II Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
 4 * 54000, SDS-PAGE Homo sapiens
216000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
colorectum increased activity in colorectal cancer cells Homo sapiens
-
liver increased activity in hepatic cancer cells Homo sapiens
-
stomach
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
9-cis-retinal + NAD+ + H2O
-
 Homo sapiens 9-cis-retinoic acid + NADH + H+
-
 ?
acetaldehyde + NAD+ + H2O
-
 Homo sapiens acetate + NADH + H+
-
 ?
aldophosphamide + NAD+ + H2O
-
 Homo sapiens ? + NADH + H+
-
 ?
all-trans-retinal + NAD+ + H2O
-
 Homo sapiens all-trans-retinoic acid + NADH + H+
-
 ?

Subunits

Subunits Comment Organism
homotetramer 4 * 54000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ALDH I
-
 Homo sapiens
ALDH II
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens