BRENDA - Enzyme Database show
show all sequences of 1.2.1.18

Enzymes of a novel autotrophic carbon dioxide fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle

Strauss, G.; Fuchs, G.; Eur. J. Biochem. 215, 633-643 (1993)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
malonyl-CoA + NADPH
Chloroflexus aurantiacus
enzyme is involved in the autotrophic CO2 fixation pathway, the 3-hydroxypropionate cycle
malonate-semialdehyde + CoA + NADP+
-
Chloroflexus aurantiacus
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Chloroflexus aurantiacus
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
malonyl-CoA + NADPH
-
288061
Chloroflexus aurantiacus
malonate-semialdehyde + CoA + NADP+
-
288061
Chloroflexus aurantiacus
?
malonyl-CoA + NADPH
enzyme is involved in the autotrophic CO2 fixation pathway, the 3-hydroxypropionate cycle
288061
Chloroflexus aurantiacus
malonate-semialdehyde + CoA + NADP+
-
288061
Chloroflexus aurantiacus
?
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
cofactor; no activity with NADH
Chloroflexus aurantiacus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
cofactor; no activity with NADH
Chloroflexus aurantiacus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
malonyl-CoA + NADPH
Chloroflexus aurantiacus
enzyme is involved in the autotrophic CO2 fixation pathway, the 3-hydroxypropionate cycle
malonate-semialdehyde + CoA + NADP+
-
Chloroflexus aurantiacus
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
malonyl-CoA + NADPH
-
288061
Chloroflexus aurantiacus
malonate-semialdehyde + CoA + NADP+
-
288061
Chloroflexus aurantiacus
?
malonyl-CoA + NADPH
enzyme is involved in the autotrophic CO2 fixation pathway, the 3-hydroxypropionate cycle
288061
Chloroflexus aurantiacus
malonate-semialdehyde + CoA + NADP+
-
288061
Chloroflexus aurantiacus
?
Other publictions for EC 1.2.1.18
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741539
Wilding
X-ray crystal structure of a ...
Pseudomonas sp., Pseudomonas sp. AAC
Acta Crystallogr. Sect. F
73
24-28
2017
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690142
Alnouti
Tissue distribution, ontogeny, ...
Mus musculus
Toxicol. Sci.
101
51-64
2008
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689379
Marchitti
Neurotoxicity and metabolism o ...
Homo sapiens
Pharmacol. Rev.
59
125-150
2007
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288061
Strauss
Enzymes of a novel autotrophic ...
Chloroflexus aurantiacus
Eur. J. Biochem.
215
633-643
1993
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288055
Goodwin
Purification and characterizat ...
Rattus norvegicus
J. Biol. Chem.
264
14965-14971
1989
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4
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288056
Waters
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A complete pathway for beta-al ...
Pseudomonas aeruginosa
FEMS Microbiol. Lett.
34
279-282
1986
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288057
Maentsaelae
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Formation of malonate-semialde ...
Pseudomonas fluorescens
Acta Chem. Scand.
1
395-396
1972
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288058
Jakoby
-
Aldehyde dehydrogenase ...
Pseudomonas sp.
The Enzymes, 2nd Ed. (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
7
203-221
1963
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288059
Hayaishi
Enzymatic studies on the metab ...
Pseudomonas fluorescens
J. Biol. Chem.
236
781-790
1961
1
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288060
Yamada
Aldehyde oxidation ...
Pseudomonas fluorescens
J. Biol. Chem.
235
589-594
1960
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