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Literature summary for 1.17.7.3 extracted from

  • Rohdich, F.; Zepeck, F.; Adam, P.; Hecht, S.; Kaiser, J.; Laupitz, R.; Grawert, T.; Amslinger, S.; Eisenreich, W.; Bacher, A.; Arigoni, D.
    The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: Studies on the mechanisms of the reactions catalyzed by IspG and isph protein (2003), Proc. Natl. Acad. Sci. USA, 100, 1586-1591.
    View publication on PubMed
Search for more literature for 1.17.7.3

Cloned(Commentary)

Cloned (Comment) Organism
recombinant fusion protein comprising maltose binding protein and IspG protein domains is expressed in Escherichia coli Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin Escherichia coli the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin
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 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli P62620
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-

Purification (Commentary)

Purification (Comment) Organism
recombinant fusion protein comprising maltose binding protein and IspG protein domains Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced 10-methyl-5-deazaisoalloxazine
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 Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized 10-methyl-5-deazaisoalloxazine
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 ?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate + reduced flavodoxin the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + oxidized flavodoxin
-
 ?

Synonyms

Synonyms Comment Organism
IspG ambiguous Escherichia coli

General Information

General Information Comment Organism
metabolism the enzyme is involved in the deoxyxylulose phosphate pathway of isoprenoid biosynthesis Escherichia coli