Literature summary for 1.17.4.2 extracted from

Yau, S.; Wachsman, J.T.
The Bacillus megaterium ribonucleotide reductase: evidence for a B 12 coenzyme requirement (1973), Mol. Cell. Biochem., 1, 101-105.

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Activating Compound

Activating Compound	Comment	Organism	Structure
ATP	required	Priestia megaterium

Inhibitors

Inhibitors	Comment	Organism	Structure
Hydroxyurea	20 mM, 20% inhibition	Priestia megaterium

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Priestia megaterium

Organism

Organism	UniProt	Comment	Textmining
Priestia megaterium	-	-	-
Priestia megaterium KM / ATCC 13632	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
CDP + reduced dithiothreitol	-	Priestia megaterium	dCDP + oxidized dithiothreitol + H2O	-	?
CDP + reduced dithiothreitol	-	Priestia megaterium KM / ATCC 13632	dCDP + oxidized dithiothreitol + H2O	-	?

Cofactor

Cofactor	Comment	Organism	Structure
coenzyme B12	required	Priestia megaterium

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Release 2023.1 (January 2023)