Inhibitors | Comment | Organism | Structure |
---|---|---|---|
allopurinol | - |
Bos taurus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0015 | - |
pterin | cell-associated enzyme, determined in intact cell monolayers | Bos taurus | |
0.0016 | - |
pterin | - |
Bos taurus | |
0.0034 | - |
xanthine | cell-associated enzyme, determined in intact cell monolayers | Bos taurus | |
0.0036 | - |
xanthine | - |
Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | enzyme binds specifically and with high affinity to bovine aortic endothelial cells, increasing cell xanthine oxidase activity up to 10fold, circulating xanthine oxidase may therefore bind to vascular cells, impairing cell function via oxidative mechanisms | Bos taurus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | iron-molybdenum protein | Bos taurus | |
Molybdenum | an iron-molybdenum protein | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
additional information | - |
Bos taurus |
proteolytic modification | - |
Bos taurus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxanthine + 2 H2O + 2 O2 | - |
Bos taurus | urate + 2 H2O2 | - |
? | |
pterin + H2O + O2 | - |
Bos taurus | isoxanthopterin + H2O2 | - |
? | |
xanthine + H2O + O2 | electron acceptor O2 | Bos taurus | uric acid + H2O2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoprotein | Bos taurus |