General Stability | Organism |
---|---|
extremely labile | Drosophila melanogaster |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.02 | - |
hypoxanthine | cosubstrate: NAD+ | Drosophila melanogaster | |
0.02 | - |
thio-NAD+ | cosubstrate: hypoxanthine | Drosophila melanogaster | |
0.0236 | - |
xanthine | cosubstrate: NAD+ | Drosophila melanogaster | |
0.025 | - |
NAD+ | cosubstrate: hypoxanthine | Drosophila melanogaster |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxanthine + NAD+ + H2O | Drosophila melanogaster | - |
xanthine + NADH + H+ | - |
? | |
xanthine + NAD+ + H2O | Drosophila melanogaster | involved in pteridine metabolism, 40% of activity compared to hypoxanthine | urate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Purification (Comment) | Organism |
---|---|
529fold purification, several (NH4)2SO4 precipitation steps | Drosophila melanogaster |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
whole body | - |
Drosophila melanogaster | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1328 | - |
- |
Drosophila melanogaster |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxanthine + NAD+ + H2O | - |
Drosophila melanogaster | xanthine + NADH + H+ | - |
? | |
hypoxanthine + thio-NAD+ + H2O | - |
Drosophila melanogaster | xanthine + thio-NADH | - |
? | |
xanthine + NAD+ + H2O | involved in pteridine metabolism, 40% of activity compared to hypoxanthine | Drosophila melanogaster | urate + NADH | - |
? | |
xanthine + thio-NAD+ + H2O | - |
Drosophila melanogaster | urate + thio-NADH | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8 | - |
- |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Drosophila melanogaster |