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Literature summary for 1.14.99.66 extracted from

  • Costa, R.; Arrigoni, G.; Cozza, G.; Lolli, G.; Battistutta, R.; Izpisua Belmonte, J.C.; Pinna, L.A.; Sarno, S.
    The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2 (2014), Biochim. Biophys. Acta, 1844, 722-729 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens O60341
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Source Tissue

Source Tissue Comment Organism Textmining
SK-N-BE(2) cell neuroblastoma cell Homo sapiens
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General Information

General Information Comment Organism
physiological function LSD1 is a substrate and an interacting partner of protein kinase CK2. The N-terminal region of LSD1 contains CK2 phosphosites Ser131, Ser137 and Ser166. This domain is not essential for LSD1 catalytic activity but may modulate the interaction with CK2 and with other partners in gene repressing and activating complexes Homo sapiens