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Literature summary for 1.14.99.4 extracted from

  • Schlenk, D.; Ronis, M.J.J.; Miranda, C.L.; Buhler, D.R.
    Channel catfish liver monooxygenases. Immunological characterization of constitutive cytochromes P450 and the absence of active flavin-containing monooxygenases (1993), Biochem. Pharmacol., 45, 217-221.
    View publication on PubMed
Search for more literature for 1.14.99.4

Application

Application Comment Organism
nutrition multiple drugs, pesticides and therapeutic agents are used in aquaculturing of channel catfish, flavin-containing monooxygenase enzymatic systems can metabolize these chemicals in the fish Ictalurus punctatus
nutrition enzyme plays a significant role in biotransformation of pesticides in rainbow trout Oncorhynchus mykiss

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Oncorhynchus mykiss
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
progesterone + NADPH + H+ + O2 Sus scrofa
-
 Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2 Oryctolagus cuniculus
-
 Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2 Oncorhynchus mykiss
-
 Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2 Ictalurus punctatus
-
 Testosterone acetate + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Ictalurus punctatus
-
 channel catfish
-
Oncorhynchus mykiss
-
 rainbow trout
-
Oryctolagus cuniculus
-
 rabbit
-
Sus scrofa
-
 pig
-

Purification (Commentary)

Purification (Comment) Organism
-
 Oncorhynchus mykiss

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Sus scrofa
-
liver
-
 Oncorhynchus mykiss
-
liver
-
 Ictalurus punctatus
-
lung
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
progesterone + NADPH + H+ + O2
-
 Sus scrofa Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2
-
 Oryctolagus cuniculus Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2
-
 Oncorhynchus mykiss Testosterone acetate + NADP+ + H2O
-
 ?
progesterone + NADPH + H+ + O2
-
 Ictalurus punctatus Testosterone acetate + NADP+ + H2O
-
 ?
testosterone + NADPH + O2
-
 Oryctolagus cuniculus 6beta-hydroxytestosterone + NADP+ + H2O
-
 ?
testosterone + NADPH + O2
-
 Ictalurus punctatus 6beta-hydroxytestosterone + NADP+ + H2O
-
 ?

Synonyms

Synonyms Comment Organism
FMO
-
 Oncorhynchus mykiss

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Oncorhynchus mykiss
cytochrome P450
-
 Ictalurus punctatus