Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.14.20.10 extracted from

  • Crawford, J.; Portmann, C.; Zhang, X.; Roeffaers, M.; Clardy, J.
    Small molecule perimeter defense in entomopathogenic bacteria (2012), Proc. Natl. Acad. Sci. USA, 109, 10821-10826 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.20.10

Application

Application Comment Organism
analysis the isonitrile functional group has a characteristic Raman resonance (observed 2121 per cm for rhabduscin) enabling observation of its cellular localization Photorhabdus laumondii subsp. laumondii

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information product rhabduscin is localized to the periphery of the recombinant overproducing Escherichia coli cells Photorhabdus laumondii subsp. laumondii
-
-

Organism

Organism UniProt Comment Textmining
Photorhabdus laumondii subsp. laumondii Q7N3A2
-
-
Photorhabdus laumondii subsp. laumondii DSM 15139 Q7N3A2
-
-
Xenorhabdus nematophila D3V9Q5
-
-
Xenorhabdus nematophila DSM 3370 D3V9Q5
-
-

Synonyms

Synonyms Comment Organism
isnB
-
 Xenorhabdus nematophila
isnB
-
 Photorhabdus laumondii subsp. laumondii
Plu2817
-
 Photorhabdus laumondii subsp. laumondii
XNC1_1222
-
 Xenorhabdus nematophila

General Information

General Information Comment Organism
physiological function deletion of IsnA-IsnB genes completely destroys isonitrile biosynthesis. Wild-type inoculation is letal in the hemolymph of Galleria mellonella larvae, while inocuation with the deletion mutant only kills half of the larvae during the experiment, and the dead larvae are generally darker compared to the wild-type–infected dead larvae Xenorhabdus nematophila
physiological function Escherichia coli cells producing IsnA, IsnB, and either glycosyltransferase GT1760 or GT1762 redundantly produce rhabduscin and a second minor glycoside, byelyankacin Photorhabdus laumondii subsp. laumondii