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Literature summary for 1.14.20.10 extracted from

  • Zhu, J.; Lippa, G.; Gulick, A.; Tipton, P.
    Examining reaction specificity in PvcB, a source of diversity in isonitrile-containing natural products (2015), Biochemistry, 54, 2659-2669 .
    View publication on PubMed
Search for more literature for 1.14.20.10

Activating Compound

Activating Compound Comment Organism Structure
ascorbate
-
 Xenorhabdus nematophila

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.013
-
 (2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate pH 7.8, 25°C Xenorhabdus nematophila
0.057
-
 2-oxoglutarate pH 7.8, 25°C Xenorhabdus nematophila

Metals/Ions

Metals/Ions Comment Organism Structure
Iron required Xenorhabdus nematophila

Organism

Organism UniProt Comment Textmining
Xenorhabdus nematophila
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2
-
 Xenorhabdus nematophila 4-[(E)-2-isocyanoethenyl]phenol + succinate + 2 CO2 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
pvcB
-
 Xenorhabdus nematophila

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
5.1
-
 2-oxoglutarate pH 7.8, 25°C Xenorhabdus nematophila

General Information

General Information Comment Organism
physiological function enzyme is onvolved in biosynthesis of paerucumarin Xenorhabdus nematophila