Literature summary for 1.14.19.53 extracted from

Kramlinger, V.; Nagy, L.; Fujiwara, R.; Johnson, K.; Phan, T.; Xiao, Y.; Enright, J.; Toomey, M.; Corbo, J.; Guengerich, F.
Human cytochrome P450 27C1 catalyzes 3,4-desaturation of retinoids (2016), FEBS Lett., 590, 1304-1312 .

Search for more literature for 1.14.19.53

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.00035	-	all-trans-retinal	pH 7.4, temperature not specified in the publication	Homo sapiens
0.0005	-	all-trans-retinol	pH 7.4, temperature not specified in the publication	Homo sapiens
0.00087	-	all-trans-retinoic acid	pH 7.4, temperature not specified in the publication	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q4G0S4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
all-trans-retinal + 2 reduced adrenodoxin + 2 H+ + O2	-	Homo sapiens	all-trans-3,4-didehydroretinal + 2 oxidized adrenodoxin + 2 H2O	-	?
all-trans-retinoic acid + 2 reduced adrenodoxin + 2 H+ + O2	-	Homo sapiens	all-trans-3,4-didehydroretinoic acid + 2 oxidized adrenodoxin + 2 H2O	-	?
all-trans-retinol + 2 reduced adrenodoxin + 2 H+ + O2	-	Homo sapiens	all-trans-3,4-didehydroretinol + 2 oxidized adrenodoxin + 2 H2O	-	?

Synonyms

Synonyms	Comment	Organism
CYP27C1	-	Homo sapiens
cytochrome P450 27C1	-	Homo sapiens

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.004	-	all-trans-retinal	pH 7.4, temperature not specified in the publication	Homo sapiens
0.023	-	all-trans-retinoic acid	pH 7.4, temperature not specified in the publication	Homo sapiens
0.38	-	all-trans-retinol	pH 7.4, temperature not specified in the publication	Homo sapiens

Cofactor

Cofactor	Comment	Organism	Structure
cytochrome P450	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)