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Literature summary for 1.14.18.1 extracted from

  • Asthana, S.; Zucca, P.; Vargiu, A.V.; Sanjust, E.; Ruggerone, P.; Rescigno, A.
    Structure-activity relationship study of hydroxycoumarins and mushroom tyrosinase (2015), J. Agric. Food Chem., 63, 7236-7244 .
    View publication on PubMed
Search for more literature for 1.14.18.1

Inhibitors

Inhibitors Comment Organism Structure
3-hydroxycoumarin
-
 Agaricus bisporus
4-Hydroxycoumarin weak inhibition Agaricus bisporus
6-hydroxycoumarin weak inhibition Agaricus bisporus
7-hydroxycoumarin
-
 Agaricus bisporus
esculetin 6,7-dihydroxycoumarin, weak inhibition Agaricus bisporus
additional information hydroxycoumarin derivatives as enzyme inhibitors, molecular docking study, structure-activity relationships, overview Agaricus bisporus
tropolone
-
 Agaricus bisporus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 L-dopa + O2 Agaricus bisporus
-
 2 dopaquinone + 2 H2O
-
 ?
tyrosine + O2 Agaricus bisporus
-
 dopaquinone + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Agaricus bisporus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 L-dopa + O2
-
 Agaricus bisporus 2 dopaquinone + 2 H2O
-
 ?
tyrosine + O2
-
 Agaricus bisporus dopaquinone + H2O
-
 ?

Synonyms

Synonyms Comment Organism
mushroom tyrosinase
-
 Agaricus bisporus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Agaricus bisporus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Agaricus bisporus