Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycolicibacterium smegmatis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lanosterol + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+ + 3 O2 | - |
Mycolicibacterium smegmatis | ? + formate + 6 oxidized ferredoxin [iron-sulfur] cluster + 4 H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 51600, SDS-PAGE | Mycolicibacterium smegmatis |
Synonyms | Comment | Organism |
---|---|---|
CYP51 | - |
Mycolicibacterium smegmatis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome P450 | the oxidized absolute spectrum of the purified CYP51, in the absence of substrate, shows a Soret band at 417 nm and alpha-, beta-, and delta-bands at 569, 535, and 369 nm | Mycolicibacterium smegmatis |
General Information | Comment | Organism |
---|---|---|
physiological function | the protein binds azole antifungals with high affinity and the rank order based on affinity matches the ranked order for microbiological sensitivity of the organism | Mycolicibacterium smegmatis |