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Literature summary for 1.14.14.150 extracted from

  • Liu, Q.; Majdi, M.; Cankar, K.; Goedbloed, M.; Charnikhova, T.; Verstappen, F.W.; de Vos, R.C.; Beekwilder, J.; van der Krol, S.; Bouwmeester, H.J.
    Reconstitution of the costunolide biosynthetic pathway in yeast and Nicotiana benthamiana (2011), PLoS ONE, 6, e23255.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expressed in yeast cells and in Nicotiana benthamiana leaves Cichorium intybus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2 Cichorium intybus
-
 (+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Cichorium intybus G3GBK0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Cichorium intybus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
germacra-1(10),4,11(13)-trien-12-oate + [reduced NADPH-hemoprotein reductase] + O2
-
 Cichorium intybus (+)-costunolide + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?

Synonyms

Synonyms Comment Organism
COS
-
 Cichorium intybus
CYP71BL3
-
 Cichorium intybus

Cofactor

Cofactor Comment Organism Structure
cytochrome P450
-
 Cichorium intybus