Cloned (Comment) | Organism |
---|---|
expressed in Saccharomyces cerevisiae | Aspergillus fumigatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | Aspergillus fumigatus | the enzyme is involved in the biosynthetic pathway of the indole alkaloid verruculogen | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? | |
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | Aspergillus fumigatus BM939 | the enzyme is involved in the biosynthetic pathway of the indole alkaloid verruculogen | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus fumigatus | B9WZX6 | - |
- |
Aspergillus fumigatus BM939 | B9WZX6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | - |
Aspergillus fumigatus | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? | |
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | the enzyme is involved in the biosynthetic pathway of the indole alkaloid verruculogen | Aspergillus fumigatus | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? | |
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | - |
Aspergillus fumigatus BM939 | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? | |
fumitremorgin C + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 | the enzyme is involved in the biosynthetic pathway of the indole alkaloid verruculogen | Aspergillus fumigatus BM939 | 12alpha,13alpha-dihydroxyfumitremorgin C + 2 [oxidized NADPH-hemoprotein reductase] + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ftmG | - |
Aspergillus fumigatus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | heme-thiolate protein (P-450) | Aspergillus fumigatus |
General Information | Comment | Organism |
---|---|---|
malfunction | the disruption of ftmG results in the loss of production of 12alpha,13alpha-dihydroxyfumitremorgin C and fumitremorgin B | Aspergillus fumigatus |
physiological function | the enzyme is involved in the biosynthetic pathway of the indole alkaloid verruculogen | Aspergillus fumigatus |