Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q91WN4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-kynurenine + NADPH + H+ + O2 | - |
Mus musculus | 3-hydroxy-L-kynurenine + NADP+ + H2O | - |
? |
General Information | Comment | Organism |
---|---|---|
malfunction | adaptiveand possibly regulatory-changes in mice with a targeted deletion of kynurenine 3-monooxygenase (Kmo-/-) are investigated kynurenine 3-monooxygenase-deficient mice are characterized using six behavioral assays relevant for the study of schizophrenia. Elimination of kynurenine 3-monooxygenase in mice is associated with multiple gene and functional alterations that appear to duplicate aspects of the psychopathology of several neuropsychiatric disorder | Mus musculus |
physiological function | adaptive-and possibly regulatory-changes in mice with a targeted deletion of kynurenine 3-monooxygenase (Kmo-/-) are investigated kynurenine 3-monooxygenase-deficient mice are characterized using six behavioral assays relevant for the study of schizophrenia. Elimination of kynurenine 3-monooxygenase in mice is associated with multiple gene and functional alterations that appear to duplicate aspects of the psychopathology of several neuropsychiatric disorder | Mus musculus |