Application | Comment | Organism |
---|---|---|
environmental protection | 2,4-dichlorophenoxy acetic acid (2,4-D) is of particular concern, as this synthetic auxin has been the most utilized herbicide in the past 50 years. It is prevalent in agricultural fields and has been widely applied in cereal crops to control broadleaved weeds. It inhibits the growth of leaf weeds by accumulating in the plant root. 2,4-D accumulated crops, on consumption, result in gastrointestinal haemorrhage, direct myocardial toxicity, CNS depression, renal failure, and other disorders. The bacterium Bacillus licheniformis strain SL10 finds potential application in the remediation of 2,4-dichlorophenol | Bacillus licheniformis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,4-dichlorophenol + NADPH + H+ + O2 | Bacillus licheniformis | - |
3,5-dichlorocatechol + NADP+ + H2O | - |
? | |
2,4-dichlorophenol + NADPH + H+ + O2 | Bacillus licheniformis MTCC 25059 | - |
3,5-dichlorocatechol + NADP+ + H2O | - |
? | |
2,4-dichlorophenol + NADPH + H+ + O2 | Bacillus licheniformis SL10 | - |
3,5-dichlorocatechol + NADP+ + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus licheniformis | - |
- |
- |
Bacillus licheniformis MTCC 25059 | - |
- |
- |
Bacillus licheniformis SL10 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2,4-dichlorophenol + NADPH + H+ + O2 | - |
Bacillus licheniformis | 3,5-dichlorocatechol + NADP+ + H2O | - |
? | |
2,4-dichlorophenol + NADPH + H+ + O2 | - |
Bacillus licheniformis MTCC 25059 | 3,5-dichlorocatechol + NADP+ + H2O | - |
? | |
2,4-dichlorophenol + NADPH + H+ + O2 | - |
Bacillus licheniformis SL10 | 3,5-dichlorocatechol + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
phenol hydroxylase | - |
Bacillus licheniformis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Bacillus licheniformis | |
NADPH | - |
Bacillus licheniformis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the catabolism of 2,4-dichlorophenol, pathways, overview | Bacillus licheniformis |
physiological function | degradation of 2,4-dichlorophenol (2,4-DCP) by phenol adapted bacterium Bacillus licheniformis strain SL10 (MTCC 25059) at a relatively fast rate. The organism exhibits tolerance to 150 ppm of 2,4-DCP and shows a linear relationship between the growth and substrate concentration, the inhibitory concentration is 55.74 mg/l, kinetics, overview. The degradation efficiency of the organism is 74% under optimum conditions but increases to 97% when the growth medium contains nil sodium chloride. The organism follows a meta-cleavage pathway while degrading 2,4-DCP | Bacillus licheniformis |