KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00415 | - |
beta-apo-8'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
0.0219 | - |
3-hydroxy-beta-apo-8'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
0.0294 | - |
beta-apo-10'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
0.0438 | - |
3-hydroxy-beta-apo-10'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | P9WPR5 | - |
- |
Mycobacterium tuberculosis H37Rv | P9WPR5 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3,3'-dihydoxyisorenieratene + O2 | 54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis | ? | - |
? | |
3,3'-dihydoxyisorenieratene + O2 | 54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
3-hydroxy-beta-apo-10'-carotenal + O2 | 3% cleavage at C15-C15' double bond, 97% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis | ? | - |
? | |
3-hydroxy-beta-apo-8'-carotenal + O2 | 95% cleavage at C15-C15' double bond, 5% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis | ? | - |
? | |
beta-apo-10'-carotenal + O2 | 79% cleavage at C13-C14 double bond, 20% cleavage at the C15-C15' double bond | Mycobacterium tuberculosis | ? | - |
? | |
beta-apo-10'-carotenal + O2 | 79% cleavage at C13-C14 double bond, 20% cleavage at the C15-C15' double bond | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
beta-apo-8'-carotenal + O2 | 86% cleavage at C13-C14 double bond, 14% cleavage at the C15-C15' double bond | Mycobacterium tuberculosis | ? | - |
? | |
beta-apo-8'-carotenal + O2 | 86% cleavage at C13-C14 double bond, 14% cleavage at the C15-C15' double bond | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
beta-carotene + O2 | 30% cleavage at C13-C14 double bond, 69% cleavage at the C15-C15' double bond | Mycobacterium tuberculosis | retinal + beta-apo-14'-carotenal + beta-apo-13-carotenone | - |
? | |
lutein + O2 | 54% cleavage at C15-C15' double bond, 45% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis | ? | - |
? | |
additional information | MtCCO cleaves the central C15-C15' and an excentric double bond at the C13-C14 position. The preference for each of the cleavage positions is determined by the hydroxylation and the nature of the ionone ring | Mycobacterium tuberculosis | ? | - |
? | |
additional information | MtCCO cleaves the central C15-C15' and an excentric double bond at the C13-C14 position. The preference for each of the cleavage positions is determined by the hydroxylation and the nature of the ionone ring | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
zeaxanthin + O2 | 83% cleavage at C15-C15' double bond, 17% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis | ? | - |
? | |
zeaxanthin + O2 | 83% cleavage at C15-C15' double bond, 17% cleavage at the C13-C14 double bond | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
carotenoid cleavage oxygenase | - |
Mycobacterium tuberculosis |
CCO | - |
Mycobacterium tuberculosis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
392 | - |
beta-apo-8'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
561 | - |
beta-apo-10'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
764 | - |
3-hydroxy-beta-apo-10'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis | |
1307 | - |
3-hydroxy-beta-apo-8'-carotenal | pH 7.9, 28°C | Mycobacterium tuberculosis |