Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | cysteine mediates the up-regulation of enzyme in cultured hepatocytes | Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | metalloenzyme | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + O2 | Rattus norvegicus | key enzyme of taurine biosynthesis, provides substrate for transamination, regulation of intracellular cysteine level | 3-sulfino-L-alanine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Sprague-Dawley rats, low enzyme level in rats fed a low protein diet, high enzyme level when low protein diet is supplemented with cysteine, homocystine, or methionine | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | primary cell culture | Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-cysteine + O2 | - |
Rattus norvegicus | 3-sulfino-L-alanine | - |
? | |
L-cysteine + O2 | key enzyme of taurine biosynthesis, provides substrate for transamination, regulation of intracellular cysteine level | Rattus norvegicus | 3-sulfino-L-alanine | - |
? |