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Literature summary for 1.1.3.9 extracted from

  • Mattey, A.; Birmingham, W.; Both, P.; Kress, N.; Huang, K.; Van Munster, J.; Bulmer, G.; Parmeggiani, F.; Voglmeir, J.; Martinez, J.; Turner, N.; Flitsch, S.
    Selective oxidation of N-glycolylneuraminic acid using an engineered galactose oxidase variant (2019), ACS Catal., 9, 8208-8212 .
No PubMed abstract available

Organism

Organism UniProt Comment Textmining
Fusarium graminearum P0CS93
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycolamide + O2
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Fusarium graminearum ? + H2O2
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?
N-glycolylneuraminic acid + O2 N-glycolylneuraminic acid can be selectively oxidized by an engineered variant of galactose oxidase without any reaction toward Neu5Ac. Neu5Gc is also oxidized when it is part of a typical animal oligosaccharide motif and when it is attached to a protein-linked N-glycan Fusarium graminearum (2R,4S,5R,6R)-2,4-dihydroxy-5-(2-oxoacetamido)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid + H2O2
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?

Synonyms

Synonyms Comment Organism
GAOA
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Fusarium graminearum
GOase
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Fusarium graminearum