Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxypregnenolone + NAD(P)H + H+ | Rattus norvegicus | - |
17alpha-hydroxyprogesterone + NAD(P)+ | - |
? | |
dehydroepiandrosterone + NAD(P)H + H+ | Rattus norvegicus | - |
androstenedione + NAD(P)+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | major site for expression | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
17alpha-hydroxypregnenolone + NAD(P)H + H+ | - |
Rattus norvegicus | 17alpha-hydroxyprogesterone + NAD(P)+ | - |
? | |
dehydroepiandrosterone + NAD(P)H + H+ | - |
Rattus norvegicus | androstenedione + NAD(P)+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3beta-HSD | - |
Rattus norvegicus |
3beta-hydroxysteroid dehydrogenase | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | 3beta-HSD is suppressed by vitamin D, about 20% at the enzyme activity level and 60% at the mRNA level | down |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is important in all basic steroidogenic pathways | Rattus norvegicus |