Inhibitors | Comment | Organism | Structure |
---|---|---|---|
GFPTGG | competitive, effects on enzyme Michaelis-Menten kinetics, overview | Rattus norvegicus | |
GLPTGG | competitive | Rattus norvegicus | |
additional information | design, synthesis and evaluation of structure-based peptide inhibitors, computational methods, overview | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.068 | - |
hydroxymethylglutaryl-CoA | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hydroxymethylglutaryl-CoA + NADPH + H+ | Rattus norvegicus | - |
mevalonate + NADP+ + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hydroxymethylglutaryl-CoA + NADPH + H+ | - |
Rattus norvegicus | mevalonate + NADP+ + CoA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HMG-CoA reductase | - |
Rattus norvegicus |
HMGR | - |
Rattus norvegicus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.023 | - |
hydroxymethylglutaryl-CoA | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0064 | - |
GFPTGG | - |
Rattus norvegicus |