Cloned (Comment) | Organism |
---|---|
gene FkSIRD, DNA and amino acid sequence determination and analysis from Forsythia genome, phylogenetic analysis, quantitative RT-PCR enzyme expression analysis | Forsythia koreana |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(-)-secoisolariciresinol + 2 NAD+ | Forsythia koreana | - |
(-)-matairesinol + 2 NADH + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Forsythia koreana | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
callus | high expression level of FkSIRD | Forsythia koreana | - |
leaf | - |
Forsythia koreana | - |
additional information | tissue- and species-specific expression of the lignan biosynthesis-related gene FkSIRD, transcriptome analysis, overview. The expression levels of DIR, PLR, SIRD, and MOMT are 40fold, 5fold, 50fold, and 2fold higher in callus than in leaf, respectively | Forsythia koreana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(-)-secoisolariciresinol + 2 NAD+ | - |
Forsythia koreana | (-)-matairesinol + 2 NADH + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FkSIRD | - |
Forsythia koreana |
matairesinol biosynthetic enzyme | - |
Forsythia koreana |
secoisolariciresinol dehydrogenase | - |
Forsythia koreana |
SirD | - |
Forsythia koreana |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Forsythia koreana |
Organism | Comment | Expression |
---|---|---|
Forsythia koreana | all of the enzymes responsible for the biosynthesis of lignan aglycones, also SIRD, are upregulated in callus | up |
General Information | Comment | Organism |
---|---|---|
evolution | molecular phylogenetic analysis of specialized metabolic enzyme genes from lignan-producing plants, two common gene clusters include genes from various plants and plant lineage-specific gene clusters. The specialized metabolic enzyme genes from lignan-producing plants include enzymes involved in the early common lignan biosynthesis upstream of matairesinol such as PLR and SIRD, suggesting that they have occurred in their ancestral plants and conserved their biological functions | Forsythia koreana |
metabolism | the enzyme is involved in the lignan biosynthesis pathway, overview | Forsythia koreana |
physiological function | matairesinol biosynthesis is prominently enhanced and matairesinol is highly accumulated in callus | Forsythia koreana |